{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T16:00:29Z","timestamp":1791475229576,"version":"4.3.4"},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:00:00Z","timestamp":1770768000000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Patients with gastric dysmotility exhibit abnormal transit and reduced contractility, for which quantification is limited with current methodologies. The Atmo Capsule is a wireless motility capsule that measures regional gastrointestinal transit. We tested its technical capabilities to evaluate gastric contractility by detecting changes in capsule acceleration during transit.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data from 91 healthy controls and 182 patients with suspected dysmotility who ingested the Atmo Capsule following a standardized protocol were included. Gastric emptying times (GET) \u2265\u20095\u2009h were considered delayed. Contraction frequencies (cycles per minute [cpm]) and amplitudes (as arbitrary units [au]) were identified following Fast Fourier Transformation of accelerometer data using 5\u2010min windows and were assessed in 30\u2010min windows post\u2010ingestion (early gastric phase) and before gastric emptying (late gastric phase). Data were compared via ANOVA, using Bonferroni corrections, between healthy controls, patients with normal gastric emptying, and patients with delayed gastric emptying.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Key Results<\/jats:title>\n                    <jats:p>\n                      Gastric emptying was delayed in 53\/182 (29%) patients. Three cpm contraction frequencies were identified across both gastric phases in controls and patients. Contraction amplitudes did not differ between groups in the early gastric phase. In the late phase, mean amplitudes were lower in patients with delayed gastric emptying (6.4\u2009au) compared with subjects with normal gastric emptying (controls, 9.7\u2009au,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001; patients, 8.6\u2009au,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions &amp; Inference<\/jats:title>\n                    <jats:p>The Atmo Capsule enables precise quantification of gastric contraction profiles, permitting differentiation of normal from pathological motor patterns. Findings of this technical assessment support its potential for evaluating gastric physiology and detecting pathophysiological patterns of gastric dysmotility.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/nmo.70255","type":"journal-article","created":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T03:14:02Z","timestamp":1770866042000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Accelerometric Assessment of Gastric Contractility Using the Atmo Wireless Motility Capsule"],"prefix":"10.1111","volume":"38","author":[{"given":"William L.","family":"Hasler","sequence":"first","affiliation":[{"name":"Gastroenterology and Hepatology Mayo Clinic  Scottsdale Arizona USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Abell","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology and Nutrition University of Louisville  Louisville Kentucky USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashok","family":"Attaluri","sequence":"additional","affiliation":[{"name":"Gastroenterology Olathe Medical Center  Olathe Kansas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William D.","family":"Chey","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology University of Michigan  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Cline","sequence":"additional","affiliation":[{"name":"Digestive Disease Institute Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard B.","family":"Gearry","sequence":"additional","affiliation":[{"name":"University of Otago  Christchurch New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9108-1712","authenticated-orcid":false,"given":"Peter R.","family":"Gibson","sequence":"additional","affiliation":[{"name":"School of Translational Medicine Monash University and Alfred Health  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3127-2933","authenticated-orcid":false,"given":"Vincent","family":"Ho","sequence":"additional","affiliation":[{"name":"Neurogastroenterology and Motility Center Hartford Healthcare  Fairfield Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allen A.","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology University of Michigan  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4479-1188","authenticated-orcid":false,"given":"Anthony J.","family":"Lembo","sequence":"additional","affiliation":[{"name":"Digestive Disease Institute Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Masoud","sequence":"additional","affiliation":[{"name":"Neurogastroenterology and Motility Center Hartford Healthcare  Fairfield Connecticut USA"},{"name":"Connecticut GI PC  Rocky Hill Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"McCallum","sequence":"additional","affiliation":[{"name":"Gastroenterology Texas Tech University Health Sciences Center  El Paso Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baharak","family":"Moshiree","sequence":"additional","affiliation":[{"name":"Advocate Health Wake Forest University  Charlotte North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eamonn M. M.","family":"Quigley","sequence":"additional","affiliation":[{"name":"Lynda K and David M Underwood Center for Digestive Health Houston Methodist Hospital and Weill Cornell Medical College  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satish S. C.","family":"Rao","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology\/Hepatology Augusta University  Augusta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayra","family":"Sanchez","sequence":"additional","affiliation":[{"name":"Neurogastroenterology and Motility Center Hartford Healthcare  Fairfield Connecticut USA"},{"name":"Connecticut GI PC  Rocky Hill Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Sarosiek","sequence":"additional","affiliation":[{"name":"Gastroenterology Texas Tech University Health Sciences Center  El Paso Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abigail","family":"Stocker","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology and Nutrition University of Louisville  Louisville Kentucky USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1139-3383","authenticated-orcid":false,"given":"Brian","family":"Surjanhata","sequence":"additional","affiliation":[{"name":"Department of Medicine, Gastroenterology Unit and Center for Neurointestinal Health, Massachusetts General Hospital Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phoebe A.","family":"Thwaites","sequence":"additional","affiliation":[{"name":"School of Translational Medicine Monash University and Alfred Health  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerry","family":"Zhou","sequence":"additional","affiliation":[{"name":"School of Medicine Western Sydney University  Campbelltown New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Braden","family":"Kuo","sequence":"additional","affiliation":[{"name":"Department of Medicine, Gastroenterology Unit and Center for Neurointestinal Health, Massachusetts General Hospital Harvard Medical School  Boston Massachusetts USA"},{"name":"Division of Digestive and Liver Diseases, Vagelos College of Physicians and Surgeons Columbia University  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,11]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2024.12.013"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2020.09.032"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.17216"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.70345"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.14438"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13196"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00119.2022"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2010.01468.x"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.2967\/jnmt.123.266799"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00274.2019"},{"key":"e_1_2_9_12_1","first-page":"3601","article-title":"Quantification of Gastric Contractions Using MRI With a Natural Contrast Agent","volume":"2021","author":"Hosseini S.","year":"2021","journal-title":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.14309\/ctg.0000000000000900"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2012.05.036"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2982.2003.00396.x"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.2967\/jnmt.118.215566"}],"container-title":["Neurogastroenterology &amp; 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