{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T17:28:28Z","timestamp":1783358908122,"version":"3.54.6"},"reference-count":37,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T00:00:00Z","timestamp":1771891200000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Wireless motility capsule (WMC) measures antroduodenal contractility and may help identify gastroparesis (GP) patients most likely to respond to gastric per\u2010oral endoscopic myotomy (G\u2010POEM). Contractile predictors of G\u2010POEM success remain elusive, and WMC contractility data have not previously been studied for this purpose.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Refractory gastroparesis patients with WMC testing prior to G\u2010POEM were retrospectively analyzed. Gastroparesis Cardinal Symptom Index (GCSI) before and after G\u2010POEM, contraction count (Ct) and area under the pressure curve (AUC) from WMC were collected 1\u2009h before and after gastric emptying time (GET). Decrease in GCSI \u2265\u20091 defined G\u2010POEM response. Antral Ct &lt;\u200929\/h, AUC &lt;\u20091358 and duodenal Ct &lt;\u200936\/h, AUC &lt;\u20091456 defined diminished contractions. Contractility between responders and non\u2010responders was compared using Pearson chi\u2010square.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Eighty\u2010five patients were analyzed (mean age 45, 88% female); 41 (48.2%) responded to G\u2010POEM. Among all patients, antroduodenal contraction parameters were not associated with G\u2010POEM response. Among idiopathic GP patients, those with preserved antral contractions by AUC were more likely to be non\u2010responders (70% vs. 30%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.028), particularly in those with severely delayed GET (74% vs. 26%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.007). Conversely, idiopathic GP patients with diminished antral contractions by AUC were more likely to be responders (67% vs. 33%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.028).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In idiopathic gastroparesis, preserved antral contractions were associated with G\u2010POEM non\u2010response, while diminished antral contractions were associated with response. Diminished antral contractions may represent a phenotype of severe motor delay responsive to \u201cpassive\u201d gastric emptying by G\u2010POEM, whereas preserved antral contractility may indicate sensory neuroenteric dysfunction less amenable to pyloric intervention.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/nmo.70276","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T09:07:33Z","timestamp":1772960853000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Preserved Antral Contractions Measured by Wireless Motility Capsule Are Associated With Lower Response Rates to Gastric Per\u2010Oral Endoscopic Myotomy in Patients With Idiopathic Gastroparesis"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6915-8557","authenticated-orcid":false,"given":"Kevin","family":"Huang","sequence":"first","affiliation":[{"name":"Division of Gastroenterology, Center for Neurointestinal Health, Massachusetts General Hospital  Boston Massachusetts USA"},{"name":"Boston University Chobanian &amp; Avedisian School of Medicine, Section of Gastroenterology and Hepatology  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1139-3383","authenticated-orcid":false,"given":"Brian","family":"Surjanhata","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Center for Neurointestinal Health, Massachusetts General Hospital  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annie","family":"Zhu","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Center for Neurointestinal Health, Massachusetts General Hospital  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingrid","family":"Guerrero\u2010Lopez","sequence":"additional","affiliation":[{"name":"School of Medicine, Universidad Europea, Villaviciosa de Od\u00f3n  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Braden","family":"Kuo","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Center for Neurointestinal Health, Massachusetts General Hospital  Boston Massachusetts USA"},{"name":"Department of Digestive Disease and Liver, Vagelos College of Medicine Columbia University  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Cline","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,24]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/17562848231151289"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102982.2008.01081.x"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13931"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.14725"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics15070935"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365521.2018.1558280"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00006.2021"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gtc.2014.11.003"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.igie.2023.07.007"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl\u20102020\u2010322756"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000003213"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2019.04.228"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13980"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.14529"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rgmxen.2018.06.004"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12522"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.22516\/25007440.1183"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2020.01.044"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.14879"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/1756283X12437874"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102982.2010.01468.x"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102982.2007.01061.x"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102982.2011.01862.x"},{"issue":"12","key":"e_1_2_11_25_1","first-page":"795","article-title":"A Technical Review and Clinical Assessment of the Wireless Motility Capsule","volume":"7","author":"Saad R. 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