{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,15]],"date-time":"2026-08-15T11:53:17Z","timestamp":1786794797997,"version":"build-2736575974"},"reference-count":35,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T00:00:00Z","timestamp":1779667200000},"content-version":"vor","delay-in-days":24,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Chronic constipation is a prevalent gastrointestinal disorder associated with substantial symptom burden and impaired quality of life. Evidence supporting synchronous physiotherapist\u2010supervised telerehabilitation in adults with chronic constipation is scarce.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Adults with chronic constipation were allocated to either a supervised telerehabilitation\u2010based exercise plus online education group (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200916) or an online education\u2010only control group (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200916). The intervention consisted of live, physiotherapist\u2010supervised exercise sessions delivered three times per week over 4\u2009weeks. Outcomes included stool consistency assessed by the Bristol Stool Form Scale, constipation severity assessed by the Constipation Assessment Scale (CAS) and Constipation Severity Instrument (CSI), disease\u2010specific quality of life assessed by the Patient Assessment of Constipation Quality of Life questionnaire (PAC\u2010QOL), and adherence.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Key Results<\/jats:title>\n                    <jats:p>\n                      By Week 4, normal stool form (Bristol Types 3\u20135) was observed in 68.8% of the intervention group and 37.5% of the control group. CAS scores were lower in the intervention group at Week 4 (3.56\u2009\u00b1\u20092.94 vs. 7.25\u2009\u00b1\u20094.33;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.008). CSI total scores also favored the intervention group (24.75\u2009\u00b1\u20099.48 vs. 37.19\u2009\u00b1\u200913.84;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.006), with greater percentage improvements in patient\u2010reported obstructive defecation, colonic inertia, pain, and total severity scores. For PAC\u2010QOL, the between\u2010group difference was significant only for satisfaction percentage change (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.008). Mean adherence was 96.9%.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and Inferences<\/jats:title>\n                    <jats:p>Adding synchronous physiotherapist\u2010supervised telerehabilitation\u2010based exercise to online education may improve stool form and patient\u2010reported constipation severity compared with education alone. These preliminary findings require confirmation in larger trials with objective physiological outcomes and longer follow\u2010up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/clinicaltrials.gov\">ClinicalTrials.gov<\/jats:ext-link>\n                      identifier: NCT05899062\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/nmo.70354","type":"journal-article","created":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T05:59:33Z","timestamp":1779775173000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Effects of a Supervised Telerehabilitation\u2010Based Exercise Program on Constipation Symptoms and Quality of Life in Adults With Chronic Constipation: A Randomized Controlled Trial"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-0991-1523","authenticated-orcid":false,"given":"\u00d6mer Faruk","family":"Can","sequence":"first","affiliation":[{"name":"Faculty of Physiotherapy and Rehabilitation Pamukkale University  Pamukkale T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1636-4082","authenticated-orcid":false,"given":"Raziye","family":"\u015eavkin","sequence":"additional","affiliation":[{"name":"Faculty of Physiotherapy and Rehabilitation Pamukkale University  Pamukkale T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2323-5756","authenticated-orcid":false,"given":"Ufuk","family":"Kutluana","sequence":"additional","affiliation":[{"name":"Sub\u2010Department of Gastroenterology, Department of Internal Medicine, School of Medicine Pamukkale University  Pamukkale T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,25]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra020995"},{"issue":"2","key":"e_1_2_13_3_1","first-page":"S3","article-title":"Definitions, Epidemiology, and Impact of Chronic Constipation","volume":"4","author":"Talley N. 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