{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T09:10:53Z","timestamp":1784365853478,"version":"3.55.0"},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The experience of emotions is accompanied by distinct bodily sensations, consistent across cultures. Irritable bowel syndrome is characterized by altered interoceptive and affective processing, suggesting that individuals with IBS may experience emotions differently in their bodies. This study investigated whether so\u2010called bodily maps of emotions differ between individuals with IBS and healthy controls (HC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Forty\u2010three individuals with IBS (Rome IV) and 54 HC used the topographical mapping tool EmBODY to color bodily silhouettes marking where sensations were perceived during 13 emotions and a neutral negative affective state. Region\u2010based (abdomen, head, thorax) and whole\u2010body pixel\u2010wise analyses were performed on the resulting body maps to compare emotion\u2010evoked sensations between individuals with IBS and HC using non\u2010parametric one\u2010way ANOVA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      IBS participants showed consistently elevated abdominal sensations across emotional states, and emotional state only modulated abdominal sensations in HC (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) but not in IBS (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.17). After correcting for neutral activation, positive emotions (love, happiness) elicited smaller increases in abdominal activation in IBS than in HC (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.03). IBS participants did not show greater abdominal activation during negative emotions relative to HC. Several positive emotions were associated with reduced head\u2010region activation in IBS (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.041), while no group differences emerged in the thorax region.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Individuals with IBS demonstrate altered embodiment of emotional states, characterized by persistent abdominal sensations, limited emotional differentiation, and blunted emotion\u2010specific modulation for positive emotions. Future studies should incorporate concurrent affect ratings and physiological measures to clarify emotion\u2013body interactions in IBS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/nmo.70366","type":"journal-article","created":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T05:56:32Z","timestamp":1780379792000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Bodily Maps of Emotions in Irritable Bowel Syndrome: A Case\u2010Control Study"],"prefix":"10.1111","volume":"38","author":[{"given":"Kato","family":"Dens","sequence":"first","affiliation":[{"name":"Department of Pediatrics University Hospitals Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maaike","family":"Van Den Houte","sequence":"additional","affiliation":[{"name":"Department of Chronic Diseases and Metabolism (CHROMETA), Laboratory for Brain\u2010Gut Axis Studies (LaBGAS), Translational Research in Gastrointestinal Disorders (TARGID) KU Leuven  Leuven Belgium"},{"name":"Leuven Brain Institute KU Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Tack","sequence":"additional","affiliation":[{"name":"Department of Chronic Diseases and Metabolism (CHROMETA), GI Motility and Sensitivity Research Group, Translational Research in Gastrointestinal Disorders (TARGID) KU Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaan","family":"Toelen","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University Hospitals Leuven  Leuven Belgium"},{"name":"Department of Development and Regeneration KU Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Dupont","sequence":"additional","affiliation":[{"name":"Leuven Brain Institute KU Leuven  Leuven Belgium"},{"name":"Department of Neurosciences, Laboratory for Cognitive Neurology KU Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lukas","family":"Van Oudenhove","sequence":"additional","affiliation":[{"name":"Department of Chronic Diseases and Metabolism (CHROMETA), Laboratory for Brain\u2010Gut Axis Studies (LaBGAS), Translational Research in Gastrointestinal Disorders (TARGID) KU Leuven  Leuven Belgium"},{"name":"Leuven Brain Institute KU Leuven  Leuven Belgium"},{"name":"Department of Psychological and Brain Sciences Cognitive and Affective Neuroscience Lab (CANlab), Dartmouth College  Hanover New Hampshire USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,1]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/44690"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.psych.58.110405.085709"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsycho.2010.03.010"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1321664111"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1037\/emo0000624"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.02.032"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.03.035"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-023-01972-w"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.13969"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00406-014-0502-z"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.5056\/jnm16220"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13514"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.14309\/ctg.0000000000000209"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41398-023-02567-3"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13143"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjhp.12250"},{"key":"e_1_2_10_18_1","unstructured":"L.NummenmaaandE.Glerean \u201cEmBODY Software \u201dhttps:\/\/version.aalto.fi\/gitlab\/eglerean\/embody."},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(25)00205-5"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jrp.2020.103964"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.5056\/jnm23159"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3999(94)90005-1"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(25)00238-9"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2009.07.005"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2024.1293150"}],"container-title":["Neurogastroenterology &amp; 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