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Bryophyte lineages were the earliest diverging embryophytes, thus being the first plants facing the <jats:styled-content style=\"fixed-case\">UV<\/jats:styled-content>\u2010B regime typical of land. We therefore examined whether liverwort and moss species have functional <jats:styled-content style=\"fixed-case\">UVR<\/jats:styled-content>8 proteins and whether they are regulated similarly to Arabidopsis <jats:styled-content style=\"fixed-case\">UVR<\/jats:styled-content>8.<\/jats:p><\/jats:list-item>\n\n<jats:list-item><jats:p>We examined the expression, dimer\/monomer status, cellular localisation and function of <jats:italic>Marchantia polymorpha<\/jats:italic> and <jats:italic>Physcomitrella patens <\/jats:italic><jats:styled-content style=\"fixed-case\">UVR<\/jats:styled-content>8 in experiments with bryophyte tissue and expression of green fluorescent protein (<jats:styled-content style=\"fixed-case\">GFP<\/jats:styled-content>)\u2013<jats:styled-content style=\"fixed-case\">UVR<\/jats:styled-content>8 fusions in <jats:italic>Nicotiana<\/jats:italic> leaves and transgenic Arabidopsis.<\/jats:p><\/jats:list-item>\n\n<jats:list-item><jats:p><jats:italic>P. patens<\/jats:italic> expresses two <jats:italic><jats:styled-content style=\"fixed-case\">UVR<\/jats:styled-content>8<\/jats:italic> genes that encode functional proteins, whereas the single <jats:italic>M.\u00a0polymorpha <jats:styled-content style=\"fixed-case\">UVR<\/jats:styled-content>8<\/jats:italic> gene expresses two transcripts by alternative splicing that encode functional <jats:styled-content style=\"fixed-case\">UVR<\/jats:styled-content>8 variants. <jats:italic>P.\u00a0patens <\/jats:italic><jats:styled-content style=\"fixed-case\">UVR<\/jats:styled-content>8 proteins form dimers that monomerise and accumulate in the nucleus following <jats:styled-content style=\"fixed-case\">UV<\/jats:styled-content>\u2010B exposure, similar to Arabidopsis <jats:styled-content style=\"fixed-case\">UVR<\/jats:styled-content>8, but <jats:italic>M.\u00a0polymorpha <\/jats:italic><jats:styled-content style=\"fixed-case\">UVR<\/jats:styled-content>8 has weaker dimers and the proteins appear more constitutively nuclear.<\/jats:p><\/jats:list-item>\n\n<jats:list-item><jats:p>We conclude that liverwort and moss species produce functional <jats:styled-content style=\"fixed-case\">UVR<\/jats:styled-content>8 proteins. Although there are differences in expression and regulation of <jats:italic>P.\u00a0patens<\/jats:italic> and <jats:italic>M.\u00a0polymorpha <\/jats:italic><jats:styled-content style=\"fixed-case\">UVR<\/jats:styled-content>8, the mechanism of <jats:styled-content style=\"fixed-case\">UVR<\/jats:styled-content>8 action is strongly conserved in evolution.<\/jats:p><\/jats:list-item>\n<\/jats:list>\n<\/jats:p>","DOI":"10.1111\/nph.14767","type":"journal-article","created":{"date-parts":[[2017,9,11]],"date-time":"2017-09-11T15:04:16Z","timestamp":1505142256000},"page":"151-162","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":65,"title":["Evolutionary conservation of structure and function of the <scp>UVR<\/scp>8 photoreceptor from the liverwort <i>Marchantia polymorpha<\/i> and the moss <i>Physcomitrella patens<\/i>"],"prefix":"10.1111","volume":"217","author":[{"given":"Gonzalo","family":"Soriano","sequence":"first","affiliation":[{"name":"Facultad de Ciencia y Tecnolog\u00eda Universidad de La Rioja Madre de Dios 53 Logro\u00f1o (La Rioja) 26006 Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Cloix","sequence":"additional","affiliation":[{"name":"Institute of Molecular Cell &amp; Systems Biology College of Medical Veterinary and Life Sciences University of Glasgow Bower Building Glasgow G12 8QQ UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"Heilmann","sequence":"additional","affiliation":[{"name":"Institute of Molecular Cell &amp; Systems Biology College of Medical Veterinary and Life Sciences University of Glasgow Bower Building Glasgow G12 8QQ 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