{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T09:42:06Z","timestamp":1790934126768,"version":"4.1.0"},"reference-count":71,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,11,21]],"date-time":"2019-11-21T00:00:00Z","timestamp":1574294400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["nph.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["New Phytologist"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>\n<jats:list list-type=\"bullet\">\n\n<jats:list-item><jats:p>Fruit defense against pathogens relies on induced and preformed mechanisms. The present contribution evaluated performed resistance of red and green mango fruit against the fungal pathogen <jats:italic>Colletotrichum gloeosporioides<\/jats:italic> and identified the main active antifungal components.<\/jats:p><\/jats:list-item>\n\n<jats:list-item><jats:p>High\u2010performance liquid chromatography analysis of nonhydrolyzed mango peel extracts identified major anthocyanin peaks of glycosylated cyanidin and methylcyanidin, and flavonol peaks of glycosylated quercetin and kaempferol, which were more abundant on the 'red side' of red mango fruit. Organic extracts of red vs green mango peel were more efficient in inhibiting <jats:italic>C.\u00a0gloeosporioides<\/jats:italic>.<\/jats:p><\/jats:list-item>\n\n<jats:list-item><jats:p>Transcriptome analysis of the mango\u2013<jats:italic>C.\u00a0gloeosporioides<\/jats:italic> interaction showed increased expression of glucosidase genes related to both fungal pathogenicity and host defense. Glucosidase treatment of organic peel extract increased its antifungal activity. Additionally, quercetin and cyanidin had significantly higher antifungal activity than their glycosylated derivatives. Peel extract volatiles treated with glucosidase had antifungal activity. GCMS analysis identified 15 volatiles after glucosidase hydrolysis, seven of them present only in red fruit.<\/jats:p><\/jats:list-item>\n\n<jats:list-item><jats:p>These results suggest that the fruit obtains a concealed arsenal of glycosylated flavonoids in its peel when they are hydrolyzed by \u03b2\u2010glucosidase that is induced in both fungus and host during infection process, become more toxic to the fungal pathogen, inhibiting decay development.<\/jats:p><\/jats:list-item>\n<\/jats:list>\n<\/jats:p>","DOI":"10.1111\/nph.16251","type":"journal-article","created":{"date-parts":[[2019,10,10]],"date-time":"2019-10-10T00:34:50Z","timestamp":1570667690000},"page":"1788-1798","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":96,"title":["Glycosylated flavonoids: fruit's concealed antifungal arsenal"],"prefix":"10.1111","volume":"225","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9025-9942","authenticated-orcid":false,"given":"Pradeep Kumar","family":"Sudheeran","sequence":"first","affiliation":[{"name":"Department of Postharvest Science of Fresh Produce Agricultural Research Organization Volcani Center PO Box 15159 HaMaccabim Road 68 Rishon LeZion 7505101 Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rinat","family":"Ovadia","sequence":"additional","affiliation":[{"name":"Department of Ornamental Plants and Agricultural Biotechnology Agricultural Research Organization Volcani Center PO Box 15159 HaMaccabim Road 68 Rishon LeZion 7505101 Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ortal","family":"Galsarker","sequence":"additional","affiliation":[{"name":"Department of Postharvest Science of Fresh Produce Agricultural Research Organization Volcani Center PO Box 15159 HaMaccabim Road 68 Rishon LeZion 7505101 Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Itay","family":"Maoz","sequence":"additional","affiliation":[{"name":"Department of Postharvest Science of Fresh Produce Agricultural Research Organization Volcani Center PO Box 15159 HaMaccabim Road 68 Rishon LeZion 7505101 Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noa","family":"Sela","sequence":"additional","affiliation":[{"name":"Department of Plant Pathology Agricultural Research Organization Volcani Center PO Box 15159 HaMaccabim Road 68 Rishon LeZion 7505101 Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dalia","family":"Maurer","sequence":"additional","affiliation":[{"name":"Department of Postharvest Science of Fresh Produce Agricultural Research Organization Volcani Center PO Box 15159 HaMaccabim Road 68 Rishon LeZion 7505101 Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oleg","family":"Feygenberg","sequence":"additional","affiliation":[{"name":"Department of Postharvest Science of Fresh Produce Agricultural Research Organization Volcani Center PO Box 15159 HaMaccabim Road 68 Rishon LeZion 7505101 Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michal","family":"Oren Shamir","sequence":"additional","affiliation":[{"name":"Department of Ornamental Plants and Agricultural Biotechnology Agricultural Research Organization Volcani Center PO Box 15159 HaMaccabim Road 68 Rishon LeZion 7505101 Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7163-6514","authenticated-orcid":false,"given":"Noam","family":"Alkan","sequence":"additional","affiliation":[{"name":"Department of Postharvest Science of Fresh Produce Agricultural Research Organization Volcani Center PO Box 15159 HaMaccabim Road 68 Rishon LeZion 7505101 Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,11,21]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/nph.13087"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.19103\/AS.2017.0026.16"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1094\/MPMI-03-13-0080-R"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.femsre.2004.11.006"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13197-012-0754-4"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkw419"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf800738r"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf0484069"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1515\/znb-2005-0718"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01874479"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00425-004-1430-3"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1078\/1439-1791-00129"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1094\/PBIOMES-05-17-0022-R"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sajb.2011.04.009"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.69.6.3258-3262.2003"},{"key":"e_1_2_7_17_1","first-page":"67","article-title":"Stress\u2010protective role of secondary metabolites: diversity of functions and mechanisms","volume":"34","author":"Edreva A","year":"2008","journal-title":"General and Applied Plant Physiology"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0048-4059(80)80017-8"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.122.2.563"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf304604v"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.postharvbio.2011.02.005"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13197-015-1963-4"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1094\/MPMI-4-415"},{"key":"e_1_2_7_24_1","first-page":"48","volume-title":"Recent advances in Botrytis research","author":"Heale JB","year":"1992"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf063452p"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.111.088732"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0434.1995.tb00246.x"},{"key":"e_1_2_7_28_1","first-page":"316","article-title":"Botrytis cinerea infection in grape flowers: defense reaction, latency, and disease expression","volume":"93","author":"Keller M","year":"2003","journal-title":"Biochemistry and Cell Biology"},{"key":"e_1_2_7_29_1","first-page":"671","article-title":"The possible role of phenolic compounds in red raspberry resistance to Didymella applanata (Niessl) Sacc","volume":"381","author":"Kozlowska M","year":"1993","journal-title":"Acta Horticulturae"},{"key":"e_1_2_7_30_1","first-page":"1","article-title":"Plant phenolics\u2010secondary metabolites with diverse functions","volume":"1","author":"Lattanzio V","year":"2008","journal-title":"Recent Advances in Polyphenol Research"},{"key":"e_1_2_7_31_1","first-page":"23","article-title":"Role of phenolics in the resistance mechanisms of plants against fungal pathogens and insects","volume":"661","author":"Lattanzio V","year":"2006","journal-title":"Phytochemistry: Advances in Research"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40694-016-0025-7"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1079\/9781845931650.0037"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp352"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2017.02.008"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-8741(01)00326-9"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-313X.1992.tb00133.x"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/0031-9422(93)85339-S"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scienta.2012.11.038"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2008.03.006"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.py.30.090192.002101"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scienta.2014.01.025"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.4172\/2329-9029.1000187"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf304349u"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2672.2001.01271.x"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btq033"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf060251c"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/0885-4505(88)90060-6"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf100848c"},{"key":"e_1_2_7_50_1","doi-asserted-by":"publisher","DOI":"10.1134\/S1068162009030133"},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.1093\/jhered\/esm128"},{"key":"e_1_2_7_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2004.07.028"},{"key":"e_1_2_7_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.postharvbio.2015.08.001"},{"key":"e_1_2_7_54_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2016.01579"},{"key":"e_1_2_7_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2013.05.053"},{"key":"e_1_2_7_56_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules23071832"},{"key":"e_1_2_7_57_1","article-title":"Anthocyanin in mango fruit peel is associated with cold and pathogen resistance","author":"Sudheeran PK","year":"2019","journal-title":"Acta Horticulturae"},{"key":"e_1_2_7_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.postharvbio.2018.11.014"},{"key":"e_1_2_7_59_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf402449q"},{"key":"e_1_2_7_60_1","first-page":"1","article-title":"Phenolic alterations in grape leaves, berries and wines due to foliar and cluster powdery mildew infections","volume":"1","author":"Taware PB","year":"2010","journal-title":"International Journal of Pharma and Bio Sciences"},{"key":"e_1_2_7_61_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0103-50532007000100011"},{"key":"e_1_2_7_62_1","doi-asserted-by":"publisher","DOI":"10.1002\/jsfa.885"},{"key":"e_1_2_7_63_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp120"},{"key":"e_1_2_7_64_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10311-006-0068-8"},{"key":"e_1_2_7_65_1","doi-asserted-by":"publisher","DOI":"10.1111\/tpj.14015"},{"key":"e_1_2_7_66_1","doi-asserted-by":"publisher","DOI":"10.1080\/17429145.2017.1316524"},{"key":"e_1_2_7_67_1","doi-asserted-by":"publisher","DOI":"10.1086\/673258"},{"key":"e_1_2_7_68_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4020-5799-1_6"},{"key":"e_1_2_7_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biotechadv.2014.04.006"},{"key":"e_1_2_7_70_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0434.2008.01488.x"},{"key":"e_1_2_7_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2013.04.072"},{"key":"e_1_2_7_72_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf060017m"}],"updated-by":[{"DOI":"10.1111\/nph.16717","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2020,6,28]],"date-time":"2020-06-28T00:00:00Z","timestamp":1593302400000}}],"container-title":["New Phytologist"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nph.16251","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/nph.16251","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/nph.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nph.16251","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T19:38:05Z","timestamp":1693856285000},"score":1,"resource":{"primary":{"URL":"https:\/\/nph.onlinelibrary.wiley.com\/doi\/10.1111\/nph.16251"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,21]]},"references-count":71,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["10.1111\/nph.16251"],"URL":"https:\/\/doi.org\/10.1111\/nph.16251","archive":["Portico"],"relation":{"correction":[{"id-type":"doi","id":"10.1111\/nph.16717","asserted-by":"object"}]},"ISSN":["0028-646X","1469-8137"],"issn-type":[{"value":"0028-646X","type":"print"},{"value":"1469-8137","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,21]]},"assertion":[{"value":"2019-08-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}