{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T06:34:45Z","timestamp":1787726085796,"version":"build-2784847793"},"reference-count":75,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,3,24]],"date-time":"2024-03-24T00:00:00Z","timestamp":1711238400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32270272"],"award-info":[{"award-number":["32270272"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32300225"],"award-info":[{"award-number":["32300225"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["nph.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["New Phytologist"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p><jats:list list-type=\"bullet\">\n<jats:list-item><jats:p>Nicotianamine (NA) plays a crucial role in transporting metal ions, including iron (Fe), in plants; therefore, <jats:italic>NICOTIANAMINE SYNTHASE<\/jats:italic> (<jats:italic>NAS<\/jats:italic>) genes, which control NA synthesis, are tightly regulated at the transcriptional level. However, the transcriptional regulatory mechanisms of <jats:italic>NAS<\/jats:italic> genes require further investigations.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>In this study, we determined the role of bZIP44 in mediating plant response to Fe deficiency stress by conducting transformation experiments and assays.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>bZIP44 positively regulated the response of Arabidopsis to Fe deficiency stress by interacting with MYB10 and MYB72 to enhance their abilities to bind at <jats:italic>NAS2<\/jats:italic> and <jats:italic>NAS4<\/jats:italic> promoters, thereby increasing <jats:italic>NAS2<\/jats:italic> and <jats:italic>NAS4<\/jats:italic> transcriptional levels and promote NA synthesis.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>In summary, the transcription activities of <jats:italic>bZIP44<\/jats:italic>, <jats:italic>MYB10<\/jats:italic>, and <jats:italic>MYB72<\/jats:italic> were induced in response to Fe deficiency stress, which enhanced the interaction between bZIP44 and MYB10 or MYB72 proteins, synergistically activated the transcriptional activity of <jats:italic>NAS2<\/jats:italic> and <jats:italic>NAS4<\/jats:italic>, promoted NA synthesis, and improved Fe transport, thereby enhancing plant tolerance to Fe deficiency stress.<\/jats:p><\/jats:list-item>\n<\/jats:list><\/jats:p>","DOI":"10.1111\/nph.19706","type":"journal-article","created":{"date-parts":[[2024,3,25]],"date-time":"2024-03-25T00:07:51Z","timestamp":1711325271000},"page":"2586-2603","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["The transcription factor <scp>bZIP44<\/scp> cooperates with <scp>MYB10<\/scp> and <scp>MYB72<\/scp> to regulate the response of <i>Arabidopsis thaliana<\/i> to iron deficiency stress"],"prefix":"10.1111","volume":"242","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0277-9754","authenticated-orcid":false,"given":"Xi","family":"Wu","sequence":"first","affiliation":[{"name":"School of Food and Biological Engineering Hefei University of Technology  Hefei 230009 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yafeng","family":"Jia","sequence":"additional","affiliation":[{"name":"School of Food and Biological Engineering Hefei University of Technology  Hefei 230009 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Ma","sequence":"additional","affiliation":[{"name":"School of Food and Biological Engineering Hefei University of Technology  Hefei 230009 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tingting","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Food and Biological Engineering Hefei University of Technology  Hefei 230009 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiena","family":"Xu","sequence":"additional","affiliation":[{"name":"School of Food and Biological Engineering Hefei University of Technology  Hefei 230009 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongli","family":"Chen","sequence":"additional","affiliation":[{"name":"Anhui Society for Horticultural Science Anhui Academy of Agricultural Sciences  Hefei 230031 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingxia","family":"Wang","sequence":"additional","affiliation":[{"name":"Institute of Horticulture Anhui Academy of Agricultural Sciences  Hefei 230031 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Song","sequence":"additional","affiliation":[{"name":"School of Food and Biological Engineering Hefei University of Technology  Hefei 230009 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6693-877X","authenticated-orcid":false,"given":"Shuqing","family":"Cao","sequence":"additional","affiliation":[{"name":"School of Food and Biological Engineering Hefei University of Technology  Hefei 230009 China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,3,24]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2024918118"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1086391"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms14047815"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1004788107"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/erab018"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/pbi.13453"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2015.11.012"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbi.2007.04.003"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/nph.18482"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abh2450"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/pce.13321"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xplc.2021.100244"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.110.159103"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-313x.1998.00343.x"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gky354"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2013.00283"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/aob\/mcn207"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-313X.2004.02128.x"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.112.107672"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbi.2018.05.001"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/eraa556"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.111.095042"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1432-1327.1999.00717.x"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00008059"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/tpj.12162"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1993.1230"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-14167-5"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1360-1385(01)02223-3"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1186\/1939-8433-6-22"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2009.244"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0141044"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.109.136374"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2018.10.439"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/tpj.15767"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.17.00821"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-313X.2005.02569.x"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-11892-5"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1093\/plcell\/koac137"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41477-021-00856-7"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.12.7098"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.110.074096"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2022.859386"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1021\/cr900112r"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1093\/plphys\/kiac357"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2023.1128002"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.04.038"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1003953"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)32594-0"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/erad057"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1093\/pcp\/pcp170"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2020.107717"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.111.088088"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2011.00069"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.112.099077"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.19.00760"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1438-8677.2008.00162.x"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12870-022-03553-5"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1111\/tpj.16130"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1080\/00380768.1999.10414350"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.107.113829"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.106.082586"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms4883"},{"key":"e_1_2_9_64_1","doi-asserted-by":"publisher","DOI":"10.1111\/jipb.13487"},{"key":"e_1_2_9_65_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11103-019-00923-w"},{"key":"e_1_2_9_66_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/erac404"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.1093\/plphys\/kiac174"},{"key":"e_1_2_9_68_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12870-014-0327-y"},{"key":"e_1_2_9_69_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1009636"},{"key":"e_1_2_9_70_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12870-019-1872-1"},{"key":"e_1_2_9_71_1","doi-asserted-by":"publisher","DOI":"10.1111\/nph.12980"},{"key":"e_1_2_9_72_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkac316"},{"key":"e_1_2_9_73_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.18.01380"},{"key":"e_1_2_9_74_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20102424"},{"key":"e_1_2_9_75_1","doi-asserted-by":"publisher","DOI":"10.1111\/jipb.12984"},{"key":"e_1_2_9_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61235-5"}],"container-title":["New Phytologist"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/nph.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nph.19706","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T10:15:10Z","timestamp":1754907310000},"score":1,"resource":{"primary":{"URL":"https:\/\/nph.onlinelibrary.wiley.com\/doi\/10.1111\/nph.19706"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,24]]},"references-count":75,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1111\/nph.19706"],"URL":"https:\/\/doi.org\/10.1111\/nph.19706","archive":["Portico"],"relation":{},"ISSN":["0028-646X","1469-8137"],"issn-type":[{"value":"0028-646X","type":"print"},{"value":"1469-8137","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,24]]},"assertion":[{"value":"2023-08-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}