{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T20:35:40Z","timestamp":1787258140593,"version":"build-2736575974"},"reference-count":63,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["lzujbky\u20102025\u2010jdzx05"],"award-info":[{"award-number":["lzujbky\u20102025\u2010jdzx05"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2024M751258"],"award-info":[{"award-number":["2024M751258"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["nph.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["New Phytologist"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    <jats:list list-type=\"bullet\">\n                      <jats:list-item>\n                        <jats:p>In eukaryotes, XERODERMA PIGMENTOSUM GROUP D (XPD) is an integral subunit of the DNA repair\/transcription complex TFIIH. In animals, XPD has been implicated in TFIIH\u2010independent complexes regulating cell division, which, however, remains poorly understood in plants.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>\n                          Here, we identified XPD as a novel regulator of stomatal development in Arabidopsis. Its loss\u2010of\u2010function mutants exhibited increased stomatal precursor cells and formed stomatal clusters. Genetic analysis showed that\n                          <jats:italic>XPD<\/jats:italic>\n                          functions upstream of\n                          <jats:italic>SPEECHLESS<\/jats:italic>\n                          (\n                          <jats:italic>SPCH<\/jats:italic>\n                          ) to control stomatal lineage entry, coordinates with\n                          <jats:italic>MUTE<\/jats:italic>\n                          to regulate meristemoid division and works together with\n                          <jats:italic>FLP<\/jats:italic>\n                          and\n                          <jats:italic>FAMA<\/jats:italic>\n                          to restrict GMC division.\n                        <\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>\n                          In a search of XPD interactors, we identified CDKA;1, which serves as both an essential cyclin\u2010dependent kinase and a key SPCH activator. Consistently,\n                          <jats:italic>xpd<\/jats:italic>\n                          mutants exhibited enhanced stomatal lineage cell divisions and elevated SPCH protein levels. Furthermore,\n                          <jats:italic>XPD<\/jats:italic>\n                          acts upstream of\n                          <jats:italic>CDKA;1<\/jats:italic>\n                          , as expression of the dominant\u2010negative\n                          <jats:italic>CDKA;1.N146<\/jats:italic>\n                          allele significantly suppressed the excessive cell division and stomatal development defects in\n                          <jats:italic>xpd<\/jats:italic>\n                          plants.\n                        <\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>Our data highlight the precise regulation of stomatal development by XPD, expanding its critical TFIIH\u2010independent roles in plant cell division and fate specification.<\/jats:p>\n                      <\/jats:list-item>\n                    <\/jats:list>\n                  <\/jats:p>","DOI":"10.1111\/nph.70915","type":"journal-article","created":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T06:54:50Z","timestamp":1770188090000},"page":"272-282","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Arabidopsis\n                    <scp>XPD<\/scp>\n                    functions upstream of\n                    <scp>CDKA<\/scp>\n                    ;1 to regulate stomatal development"],"prefix":"10.1111","volume":"250","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-5948-2547","authenticated-orcid":false,"given":"Ping","family":"Li","sequence":"first","affiliation":[{"name":"Gansu Province Key Laboratory of Gene Editing for Breeding, Ministry of Education on Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences Lanzhou University  Lanzhou 730000 China"},{"name":"College of Grassland Agricultural Science and Technology Lanzhou University  Lanzhou 730000 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-9910-1380","authenticated-orcid":false,"given":"Xiaoli","family":"Gu","sequence":"additional","affiliation":[{"name":"Gansu Province Key Laboratory of Gene Editing for Breeding, Ministry of Education on Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences Lanzhou University  Lanzhou 730000 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6313-0521","authenticated-orcid":false,"given":"Jiangwei","family":"Luo","sequence":"additional","affiliation":[{"name":"Gansu Province Key Laboratory of Gene Editing for Breeding, Ministry of Education on Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences Lanzhou University  Lanzhou 730000 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-2181-6110","authenticated-orcid":false,"given":"Mingfeng","family":"Zhao","sequence":"additional","affiliation":[{"name":"Gansu Province Key Laboratory of Gene Editing for Breeding, Ministry of Education on Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences Lanzhou University  Lanzhou 730000 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5926-2659","authenticated-orcid":false,"given":"Wenjin","family":"Wang","sequence":"additional","affiliation":[{"name":"Gansu Province Key Laboratory of Gene Editing for Breeding, Ministry of Education on Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences Lanzhou University  Lanzhou 730000 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2057-4370","authenticated-orcid":false,"given":"Longfeng","family":"Yan","sequence":"additional","affiliation":[{"name":"Gansu Province Key Laboratory of Gene Editing for Breeding, Ministry of Education on Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences Lanzhou University  Lanzhou 730000 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7687-8256","authenticated-orcid":false,"given":"Zhipeng","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Grassland Agricultural Science and Technology Lanzhou University  Lanzhou 730000 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1548-2885","authenticated-orcid":false,"given":"Liang","family":"Chen","sequence":"additional","affiliation":[{"name":"Gansu Province Key Laboratory of Gene Editing for Breeding, Ministry of Education on Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences Lanzhou University  Lanzhou 730000 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1961-4216","authenticated-orcid":false,"given":"Suiwen","family":"Hou","sequence":"additional","affiliation":[{"name":"Gansu Province Key Laboratory of Gene Editing for Breeding, Ministry of Education on Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences Lanzhou University  Lanzhou 730000 China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,3]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2015.01.025"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.arplant.58.032806.104023"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.26508\/lsa.201800197"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature01746"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2020.00114"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biochem-060815-014857"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abp9457"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbi.2008.09.012"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00390212"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/jexbot\/51.351.1647"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41477-020-00770-4"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.15252\/embj.2020105802"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41477-020-00804-x"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.13.6488"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2008.04.030"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-313X.2010.04317.x"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.12.11.2075"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbi.2022.102257"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/nph.17613"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.110.167718"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11105-008-0076-x"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41477-020-00809-6"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2018.04.010"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbi.2019.03.010"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/plphys\/kiaa061"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-018-0714-x"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dnarep.2016.05.019"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2010.07.029"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.115.4.1351"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-313X.2004.02004.x"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1534\/g3.112.003368"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/bs.apcsb.2019.01.003"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tplants.2017.11.008"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.105.034116"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.105.062257"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1256888"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-arplant-050718-100251"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/tpj.12516"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/tpj.12489"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/tpj.16146"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.103.021808"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plantsci.2013.09.004"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature05491"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.03271"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1199\/tab.0066"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2012.02.015"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.106.046136"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature05467"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-arplant-042811-105451"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1111\/dgd.12282"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1004464"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mrrev.2008.07.003"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/16.7.1628"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1093\/plcell\/koab222"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M113.029256"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/erab034"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.160671"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1105\/tpc.110.074609"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/eru139"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molp.2014.12.014"},{"key":"e_1_2_9_62_1","first-page":"2227","article-title":"The too many mouths and four lips mutations affect stomatal production in Arabidopsis","volume":"7","author":"Yang M","year":"1995","journal-title":"Plant Cell"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2014.202"},{"key":"e_1_2_9_64_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1919722117"}],"container-title":["New Phytologist"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/nph.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nph.70915","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/nph.onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/nph.70915","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/nph.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nph.70915","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T23:25:58Z","timestamp":1773012358000},"score":1,"resource":{"primary":{"URL":"https:\/\/nph.onlinelibrary.wiley.com\/doi\/10.1111\/nph.70915"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,3]]},"references-count":63,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1111\/nph.70915"],"URL":"https:\/\/doi.org\/10.1111\/nph.70915","archive":["Portico"],"relation":{},"ISSN":["0028-646X","1469-8137"],"issn-type":[{"value":"0028-646X","type":"print"},{"value":"1469-8137","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,3]]},"assertion":[{"value":"2025-10-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}