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Much of\n                    <jats:italic>C. ohadii<\/jats:italic>\n                    's appeal as an emerging model lies in its robust fast growth, comparable to yeast even as a photoautotroph. Hence, the detailed physiological, biochemical, and molecular studies that followed rapidly, together with extensive omics datasets, have revealed several of its intriguing biological features. We provide a historical perspective unfolding the rise of this species from survival in the harsh desert crusts to a widely used standard for photodamage resistance, dynamic metabolism, and elevated growth and photosynthetic performance, frequently with prominent relevance for plant research. We also spotlight how this case study enables exploration of photosynthesis in harsh habitats. Further, we discuss challenges in the development of genetic tools for the growing community studying\n                    <jats:italic>C.\u00a0ohadii<\/jats:italic>\n                    , and current biotechnological approaches aiming to exploit its prime genetic potential. Finally, we refer to guidelines of good practice for\n                    <jats:italic>C. ohadii<\/jats:italic>\n                    research as a highly stress\u2010resistant model.\n                  <\/jats:p>","DOI":"10.1111\/nph.71587","type":"journal-article","created":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T08:30:52Z","timestamp":1790843452000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Extending the limits of algal growth and stress resilience\u2009\u2013\u2009the desert alga\n                    <scp>\n                      <i>Chlorella ohadii<\/i>\n                    <\/scp>\n                    as an emerging model"],"prefix":"10.1111","author":[{"given":"Or","family":"Geffen","sequence":"first","affiliation":[{"name":"Systems Plant Metabolism, Faculty of Biology RPTU  67663 Kaiserslautern Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hilla","family":"Matityahu","sequence":"additional","affiliation":[{"name":"Department of Plant and Environmental Sciences, The Alexander Silberman Institute of Life Sciences The Hebrew University of Jerusalem  91904 Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0177-0624","authenticated-orcid":false,"given":"Iftach","family":"Yacoby","sequence":"additional","affiliation":[{"name":"School of Plant Sciences and Food Security, The George S. Wise Faculty of Life Sciences Tel Aviv University  Ramat Aviv 97801 Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6280-3122","authenticated-orcid":false,"given":"Michal","family":"Breker","sequence":"additional","affiliation":[{"name":"Department of Plant and Environmental Sciences, The Alexander Silberman Institute of Life Sciences The Hebrew University of Jerusalem  91904 Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3431-6965","authenticated-orcid":false,"given":"Haim","family":"Treves","sequence":"additional","affiliation":[{"name":"Systems Plant Metabolism, Faculty of Biology RPTU  67663 Kaiserslautern Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,1]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbabio.2017.07.001"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/erw414"},{"key":"e_1_2_12_4_1","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1038\/s41467-025-65861-2","article-title":"Cryo\u2010EM structure of photosystem II supercomplex from a green microalga with extreme phototolerance","volume":"17","author":"Arshad R","year":"2026","journal-title":"Nature Communications"},{"key":"e_1_2_12_5_1","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2601363123","article-title":"Nocturnal hydration prepares desert cyanobacteria for dawn\u2010light harvesting by inducing phycoerythrin synthesis","volume":"123","author":"Bai Y","year":"2026","journal-title":"Proceedings of the National Academy of Sciences, 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