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While the general etiology of cerebral ischemia and stroke has been known for some time, the conditions have only recently been considered treatable. This report describes current research in this field seeking to fully understand the pathomechanisms underlying stroke; to characterize the brain's intrinsic injury, survival, and repair mechanisms; to identify putative drug targets as well as cell\u2010based therapies; and to optimize the delivery of therapeutic agents to the damaged cerebral tissue.<\/jats:p>","DOI":"10.1111\/nyas.12087","type":"journal-article","created":{"date-parts":[[2013,3,13]],"date-time":"2013-03-13T21:28:54Z","timestamp":1363210134000},"page":"25-32","source":"Crossref","is-referenced-by-count":23,"title":["Neuroprotection after cerebral ischemia"],"prefix":"10.1111","volume":"1278","author":[{"given":"Shobu","family":"Namura","sequence":"first","affiliation":[{"name":"Neuroscience Institute, Department of Neurobiology Morehouse School of Medicine Atlanta Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroaki","family":"Ooboshi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Fukuoka Dental College Medical and Dental Hospital Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jialing","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Midori A.","family":"Yenari","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of California San Francisco, and The San Francisco Veterans Affairs Medical Center San Francisco California"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,3,11]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2010.12.004"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12975-010-0046-0"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2012.04.007"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2011.03081.x"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jcbfm.9600212"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0007247"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2012.08.002"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2011.07.016"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.2174\/156720212799297100"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2010.03.003"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.2012.3"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.90656.2008"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.2009.185"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.110.592865"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2749"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2009.06042.x"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.2010.32"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.111.637884"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2011.06.006"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth844"}],"container-title":["Annals of the New York Academy of Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fnyas.12087","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/nyaspubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nyas.12087","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T11:13:32Z","timestamp":1695986012000},"score":1,"resource":{"primary":{"URL":"https:\/\/nyaspubs.onlinelibrary.wiley.com\/doi\/10.1111\/nyas.12087"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,3]]}},"alternative-id":["10.1111\/nyas.12087"],"URL":"https:\/\/doi.org\/10.1111\/nyas.12087","archive":["Portico"],"relation":{},"ISSN":["0077-8923","1749-6632"],"issn-type":[{"value":"0077-8923","type":"print"},{"value":"1749-6632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3]]}}}