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In Asian patients, diabetes develops at a younger age and is characterized by early \u03b2 cell dysfunction in the setting of insulin resistance, with many requiring early insulin treatment. The increasing proportion of young\u2010onset and childhood type 2 diabetes is posing a particular threat, with these patients being at increased risk of developing diabetic complications. East Asian patients with type 2 diabetes have a higher risk of developing renal complications than Europeans and, with regard to cardiovascular complications, a predisposition for developing strokes. In addition to cardiovascular\u2013renal disease, cancer is emerging as the other main cause of mortality. While more research is needed to explain these interethnic differences, urgent and concerted actions are needed to raise awareness, facilitate early diagnosis, and encourage preventive strategies to combat these growing disease burdens.<\/jats:p>","DOI":"10.1111\/nyas.12098","type":"journal-article","created":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T14:10:05Z","timestamp":1364825405000},"page":"64-91","source":"Crossref","is-referenced-by-count":780,"title":["Type 2 diabetes in East Asians: similarities and differences with populations in Europe and the United States"],"prefix":"10.1111","volume":"1281","author":[{"given":"Ronald C.W.","family":"Ma","sequence":"first","affiliation":[{"name":"Department of Medicine and Therapeutics Hong Kong Institute of Diabetes and Obesity Li Ka Shing Institute of Health Sciences The Chinese University of Hong Kong The Prince of Wales Hospital  Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana 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