{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T03:11:14Z","timestamp":1785294674403,"version":"3.55.0"},"reference-count":78,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,6,10]],"date-time":"2015-06-10T00:00:00Z","timestamp":1433894400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"CONACYT","award":["253053"],"award-info":[{"award-number":["253053"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of the New York Academy of Sciences"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:p>Recent studies suggest that catecholamines (CAs) and acetylcholine (ACh) play essential roles in the crosstalk between microbes and the immune system. Host cholinergic afferent fibers sense pathogen\u2010associated molecular patterns and trigger efferent cholinergic and catecholaminergic pathways that alter immune cell proliferation, differentiation, and cytokine production. On the other hand, microbes have the ability to produce and degrade ACh and also regulate autogenous functions in response to CAs. Understanding the role played by these neurotransmitters in host\u2013microbe interactions may provide valuable information for the development of novel therapies.<\/jats:p>","DOI":"10.1111\/nyas.12792","type":"journal-article","created":{"date-parts":[[2015,6,19]],"date-time":"2015-06-19T14:07:02Z","timestamp":1434722822000},"page":"39-51","source":"Crossref","is-referenced-by-count":32,"title":["Catecholamines and acetylcholine are key regulators of the interaction between microbes and the immune system"],"prefix":"10.1111","volume":"1351","author":[{"given":"Leon","family":"Islas Weinstein","sequence":"first","affiliation":[{"name":"Department of Pathology, Experimental Pathology Section The Salvador Zubir\u00e1n National Institute of Medical Sciences and Nutrition  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Revuelta","sequence":"additional","affiliation":[{"name":"Department of Pathology, Experimental Pathology Section The Salvador Zubir\u00e1n National Institute of Medical Sciences and Nutrition  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rogelio Hernandez","family":"Pando","sequence":"additional","affiliation":[{"name":"Department of Pathology, Experimental Pathology Section The Salvador Zubir\u00e1n National Institute of Medical Sciences and Nutrition  Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,6,10]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1242\/dmm.003871"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2009.09.039"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri2566"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.3144"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0024-3205(02)01740-X"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0024-3205(02)02478-5"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2006.114926"},{"key":"e_1_2_10_9_1","first-page":"1","volume-title":"Human Physiology: An Integrated Approach","author":"Silverthorn D.U.","year":"2009"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-0082(97)00050-6"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1369\/jhc.6A7168.2007"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2567.1996.d01-653.x"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.2119\/2007-00105.Flierl"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0004414"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0024-3205(00)00937-1"},{"key":"e_1_2_10_16_1","doi-asserted-by":"crossref","first-page":"2745","DOI":"10.1128\/AAC.42.10.2745","article-title":"Enhancement of antimicrobial activity of neuropeptide and by N\u2010terminal truncation","volume":"42","author":"Shimizu M.","year":"1998","journal-title":"Antimicrob. Agents Chemother."},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2010.10.019"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.166.1.232"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5728(96)00004-5"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2005.06.007"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2011.08.001"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.162.9.5299"},{"key":"e_1_2_10_23_1","doi-asserted-by":"crossref","first-page":"111","DOI":"10.3233\/NIB-2012-012044","article-title":"Role of peripheral and brain\u2010derived dopamine (DA) in immune regulation","volume":"3","author":"T\u00f3th B.E.","year":"2012","journal-title":"Adv. Neuroimmune Biol."},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00630-07"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2012.06516.x"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1221655110"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0065936"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-1-3-279"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02858764"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12031-013-0172-8"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnmol.2012.00066"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1271\/bbb1961.39.105"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4522(02)00223-3"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0902212"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/0147-9571(94)90009-4"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1681.1999.03016.x"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exppara.2010.01.006"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-23274-9"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2004.09.002"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1023\/B:NERE.0000035801.81825.2a"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v8.i3.540"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00487.2010"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jit669"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1113\/expphysiol.2012.066431"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1102999108"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1159\/000081766"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.5.2274"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.69.12.7234-7241.2001"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.065607-0"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-2614"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/283525"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20052362"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0901808"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellimm.2004.07.007"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00103408"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.11-197384"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.167.11.6518"},{"key":"e_1_2_10_58_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.11-191007"},{"key":"e_1_2_10_59_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1209985"},{"key":"e_1_2_10_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1838(94)90047-7"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.2119\/molmed.2011.00405"},{"key":"e_1_2_10_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autneu.2014.01.006"},{"key":"e_1_2_10_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2014.07.010"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.1113\/expphysiol.2011.061531"},{"key":"e_1_2_10_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2014.02.011"},{"key":"e_1_2_10_66_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.a.20093"},{"key":"e_1_2_10_67_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1210301"},{"key":"e_1_2_10_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autneu.2013.12.003"},{"key":"e_1_2_10_69_1","doi-asserted-by":"publisher","DOI":"10.1002\/jemt.20135"},{"key":"e_1_2_10_70_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01203-09"},{"key":"e_1_2_10_71_1","first-page":"285","article-title":"Effect of norepinephrine on growth of Salmonella and its enterotoxin production","volume":"38","author":"Rahman H.","year":"2000","journal-title":"Indian J. Exp. Biol."},{"key":"e_1_2_10_72_1","doi-asserted-by":"publisher","DOI":"10.1086\/513275"},{"key":"e_1_2_10_73_1","first-page":"709","article-title":"Electrophysiological identification of vagally innervated enteric neurons in guinea pig stomach","volume":"263","author":"Schemann M.","year":"1992","journal-title":"Am. J. Physiol."},{"key":"e_1_2_10_74_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni1229"},{"key":"e_1_2_10_75_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0109272"},{"key":"e_1_2_10_76_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3479"},{"key":"e_1_2_10_77_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.72.9.5446-5451.2004"},{"key":"e_1_2_10_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5728(02)00321-1"},{"key":"e_1_2_10_79_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2009.04.057"}],"container-title":["Annals of the New York Academy of Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fnyas.12792","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fnyas.12792","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/nyaspubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nyas.12792","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T04:20:36Z","timestamp":1695874836000},"score":1,"resource":{"primary":{"URL":"https:\/\/nyaspubs.onlinelibrary.wiley.com\/doi\/10.1111\/nyas.12792"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6,10]]},"references-count":78,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,9]]}},"alternative-id":["10.1111\/nyas.12792"],"URL":"https:\/\/doi.org\/10.1111\/nyas.12792","archive":["Portico"],"relation":{},"ISSN":["0077-8923","1749-6632"],"issn-type":[{"value":"0077-8923","type":"print"},{"value":"1749-6632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,6,10]]}}}