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The seizure\u2010inducing rodenticide tetramethylenedisulfotetramine is one of the most toxic of these agents. Although banned, it has been responsible for thousands of accidental, intentional, and mass poisonings in mainland China and elsewhere. An optimal regimen for treatment of poisoning has not been established. Its facile synthesis from easily obtained starting materials, extreme potency, and lack of odor, color, or taste make it a potential chemical threat agent. This review describes the toxicologic properties of this agent, more recent advances in our understanding of its properties, and recommendations for future research.<\/jats:p>","DOI":"10.1111\/nyas.13120","type":"journal-article","created":{"date-parts":[[2016,7,6]],"date-time":"2016-07-06T17:46:31Z","timestamp":1467827191000},"page":"68-79","source":"Crossref","is-referenced-by-count":7,"title":["Tetramethylenedisulfotetramine: pest control gone awry"],"prefix":"10.1111","volume":"1378","author":[{"given":"Michael P.","family":"Shakarjian","sequence":"first","affiliation":[{"name":"Department of Environmental Health Science, School of Health Sciences and Practice, Institute of Public Health New York Medical College Valhalla New York"},{"name":"Department of Cell Biology and Anatomy New York Medical College Valhalla New York"},{"name":"Department of Medicine, Division of Pulmonary and Critical Care Medicine Rutgers\u2010Robert Wood Johnson Medical School Piscataway New Jersey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcela","family":"Laukova","sequence":"additional","affiliation":[{"name":"Department of Environmental Health Science, School of Health Sciences and Practice, Institute of Public Health New York Medical College Valhalla New York"},{"name":"Institute of Experimental Endocrinology Biomedical Research Center, Slovak Academy of Sciences Bratislava Slovakia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jana","family":"Vel\u00ed\u0161kov\u00e1","sequence":"additional","affiliation":[{"name":"Department of Cell Biology and Anatomy New York Medical College Valhalla New York"},{"name":"Department of Obstetrics and Gynecology New York Medical College Valhalla New York"},{"name":"Department of Neurology New York Medical College Valhalla New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patric K.","family":"Stanton","sequence":"additional","affiliation":[{"name":"Department of Cell Biology and Anatomy New York Medical College Valhalla New York"},{"name":"Department of Neurology New York Medical College Valhalla New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diane E.","family":"Heck","sequence":"additional","affiliation":[{"name":"Department of Environmental Health Science, School of Health Sciences and Practice, Institute of Public Health New York Medical College Valhalla New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Libor","family":"Vel\u00ed\u0161ek","sequence":"additional","affiliation":[{"name":"Department of Cell Biology and Anatomy New York Medical College Valhalla New York"},{"name":"Department of Neurology New York Medical College Valhalla New York"},{"name":"Department of Pediatrics New York Medical College Valhalla New York"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,7,6]]},"reference":[{"key":"e_1_2_14_2_1","unstructured":"NIOSH.2015.Pesticide illness & injury surveillance. 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