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There is evidence that sensory deficits in those populations are closely related to swallowing disorders, and several research groups are developing new therapies based on sensory stimulation of this area. More information on the sensory innervation participating in the swallow response is needed to better understand the pathophysiology of OD and to develop new treatments. This review focuses on the sensory innervation of the human oropharynx and larynx in healthy people compared with patients with swallowing disorders in order to unravel the abnormalities that may lead to the loss of sensitivity in patients with OD. We also hypothesize the pathway through which active sensory\u2010enhancement treatments may elicit their therapeutic effect on patients with swallowing dysfunctions. As far as we know, this is the first time a review covers the anatomy, histology, ultrastructure, and molecular biology of the sensory innervation of the swallowing function.<\/jats:p>","DOI":"10.1111\/nyas.13150","type":"journal-article","created":{"date-parts":[[2016,7,21]],"date-time":"2016-07-21T19:18:41Z","timestamp":1469128721000},"page":"104-120","source":"Crossref","is-referenced-by-count":47,"title":["Oropharyngeal and laryngeal sensory innervation in the pathophysiology of swallowing disorders and sensory stimulation treatments"],"prefix":"10.1111","volume":"1380","author":[{"given":"Daniel","family":"Alvarez\u2010Berdugo","sequence":"first","affiliation":[{"name":"Gastrointestinal Motility Laboratory, Hospital de Matar\u00f3 Consorci Sanitari del Maresme  Matar\u00f3 Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas Instituto de Salud Carlos III  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laia","family":"Rofes","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas Instituto de Salud Carlos III  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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