{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T08:12:03Z","timestamp":1694679123209},"reference-count":53,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,7,21]],"date-time":"2016-07-21T00:00:00Z","timestamp":1469059200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of the New York Academy of Sciences"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:p>Treatment of esophageal pain remains a major challenge for the clinician. Although many patients have heartburn and may respond to proton pump inhibitors, there in an unmet need for other treatment modalities in patients where there are no obvious pathological findings. Although analgesics are the mainstay in esophageal pain treatment, many patients are nonresponders to these drugs. The current concise review focuses on other systems affecting pain processing, where better understanding may serve as a framework for therapy. These are the parasympathetic nervous system, exercise, and personality profiles. Finally, treatment with analgesics for functional chest pain remains a challenge, and an overview of treatment with antidepressive drugs is provided.<\/jats:p>","DOI":"10.1111\/nyas.13151","type":"journal-article","created":{"date-parts":[[2016,7,21]],"date-time":"2016-07-21T19:17:46Z","timestamp":1469128666000},"page":"58-66","source":"Crossref","is-referenced-by-count":1,"title":["Pharmacological and other treatment modalities for esophageal pain"],"prefix":"10.1111","volume":"1380","author":[{"given":"Dag Arne Lihaug","family":"Hoff","sequence":"first","affiliation":[{"name":"Clinic of Medicine HMR Hospital Trust, Department of Medicine, Division of Gastroenterology &amp; Hepatology Aalesund Hospital  Aalesund Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina","family":"Brock","sequence":"additional","affiliation":[{"name":"Mech\u2010Sense, Department of Gastroenterology &amp; Hepatology, Aalborg University Hospital and Clinical Institute Aalborg University  Aalborg Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam D.","family":"Farmer","sequence":"additional","affiliation":[{"name":"Mech\u2010Sense, Department of Gastroenterology &amp; Hepatology, Aalborg University Hospital and Clinical Institute Aalborg University  Aalborg Denmark"},{"name":"Centre for Digestive Diseases, Blizard Institute, Wingate Institute of Neurogastroenterology, Barts and the London School of Medicine &amp; Dentistry Queen Mary University of London  London United Kingdom"},{"name":"Department of Gastroenterology University Hospitals of North Midlands  Stoke on Trent United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ram","family":"Dickman","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Rabin Medical Center, Beilinson Campus, Petach Tikva &amp; Sackler School of Medicine University of Tel Aviv  Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James K.","family":"Ruffle","sequence":"additional","affiliation":[{"name":"Centre for Digestive Diseases, Blizard Institute, Wingate Institute of Neurogastroenterology, Barts and the London School of Medicine &amp; Dentistry Queen Mary University of London  London United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anisa","family":"Shaker","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Gastrointestinal and Liver Diseases, University of Southern California Keck School of Medicine  Los Angeles California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asbj\u00f8rn M.","family":"Drewes","sequence":"additional","affiliation":[{"name":"Mech\u2010Sense, Department of Gastroenterology &amp; Hepatology, Aalborg University Hospital and Clinical Institute Aalborg University  Aalborg Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,7,21]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12817"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12785"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autneu.2013.12.007"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1366.014"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2013-304676"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/35013070"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2006.08.016"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12792"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12245"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02758-6"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2012.01929.x"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2013-306698"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.13145"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2012.09.006"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005768-199611000-00011"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2007.06.003"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/pme.12312"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1519\/JSC.0b013e3181a05564"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2013.05.016"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2009.01304.x"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-382026-6.00023-3"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.2190\/RFUR-TA4R-KXPB-18FL"},{"key":"e_1_2_9_24_1","volume-title":"Dimensions of Personality","author":"Eysenck H.J.","year":"1947"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.paid.2014.10.024"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2011.06.008"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12760"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2012.04.006"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4637.2012.01385.x"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4637.2011.01243.x"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11916-012-0312-9"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1023\/B:JOBM.0000019849.21524.70"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.08.060"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2010.01555.x"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(99)00344-7"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00200.2012"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.2001.281.5.G1196"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365520500442559"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.2190\/PM.38.3.d"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365520310004399"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v12.i16.2477"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2012.05103.x"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1097\/PSY.0000000000000257"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2011.04904.x"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.1997.0615"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v19.i30.4958"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1177\/0091270010394852"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1067\/mhj.2000.108514"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2006.02772.x"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.13015"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2010.04561.x"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1021017524660"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11894-014-0390-4"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2008.03859.x"}],"container-title":["Annals of the New York Academy of Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fnyas.13151","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/nyaspubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nyas.13151","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T04:43:19Z","timestamp":1694580199000},"score":1,"resource":{"primary":{"URL":"https:\/\/nyaspubs.onlinelibrary.wiley.com\/doi\/10.1111\/nyas.13151"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,21]]},"references-count":53,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["10.1111\/nyas.13151"],"URL":"https:\/\/doi.org\/10.1111\/nyas.13151","archive":["Portico"],"relation":{},"ISSN":["0077-8923","1749-6632"],"issn-type":[{"value":"0077-8923","type":"print"},{"value":"1749-6632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7,21]]}}}