{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T13:28:25Z","timestamp":1783949305285,"version":"3.55.0"},"reference-count":78,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,9,7]],"date-time":"2016-09-07T00:00:00Z","timestamp":1473206400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","award":["MEMENTO, FP7\u2010PEOPLE\u20102011\u2010IOF"],"award-info":[{"award-number":["MEMENTO, FP7\u2010PEOPLE\u20102011\u2010IOF"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of the New York Academy of Sciences"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:p>Can environmental factors, such as air\u2010transported preformed toxins, be of key relevance to the health outcomes of poorly understood human ailments (e.g., rheumatic diseases such as vasculitides, some inflammatory diseases, or even severe childhood acquired heart diseases)? Can the physical, chemical, or biological features of air masses be linked to the emergence of diseases such as Kawasaki disease (KD), Henoch\u2013Sch\u00f6nlein purpura, Takayasu's aortitis, and ANCA\u2010associated vasculitis? These diseases surprisingly share some common epidemiological features. For example, they tend to appear as clusters of cases grouped geographically and temporarily progress in nonrandom sequences that repeat every year in a similar way. They also show concurrent trend changes within regions in countries and among different world regions. In this paper, we revisit transdisciplinary research on the role of environmental and climate factors in the epidemiology of KD as a paradigmatic example of this group of diseases. Early\u2010warning systems based on environmental alerts, if successful, could be implemented as a way to better inform patients who are predisposed to, or at risk for, developing KD. Further research on the etiology of KD could facilitate the development of vaccines and specific medical therapies.<\/jats:p>","DOI":"10.1111\/nyas.13201","type":"journal-article","created":{"date-parts":[[2016,9,7]],"date-time":"2016-09-07T22:47:04Z","timestamp":1473288424000},"page":"84-98","source":"Crossref","is-referenced-by-count":31,"title":["Revisiting the role of environmental and climate factors on the epidemiology of Kawasaki disease"],"prefix":"10.1111","volume":"1382","author":[{"given":"Xavier","family":"Rod\u00f3","sequence":"first","affiliation":[{"name":"Institut Catal\u00e0 de Ci\u00e8ncies del Clima (IC3)"},{"name":"Instituci\u00f3 Catalana de Recerca i Estudis Avan\u00e7ats (ICREA) Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan","family":"Ballester","sequence":"additional","affiliation":[{"name":"Institut Catal\u00e0 de Ci\u00e8ncies del Clima 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