{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T14:46:47Z","timestamp":1768747607640,"version":"3.49.0"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,1,31]],"date-time":"2017-01-31T00:00:00Z","timestamp":1485820800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of the New York Academy of Sciences"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:p>High\u2010resolution manometry (HRM) is currently the most important diagnostic test for esophageal motility disorders, providing information on the contraction pattern of the circular muscle layer, which helps classify these esophageal motor diseases. However, with the increasing development of ultrasound, other techniques, such as high\u2010frequency intraluminal ultrasound (HFIUS), have gained importance. This technique uses a flexible shaft with a central wire integrated into a standard endoscope, which facilitates real\u2010time sonography. Its main utility is to provide anatomical information on the structure of the esophageal wall, including both the circular and longitudinal layers that constitute the esophageal muscularis propria. Increasing knowledge about these motility disorders has led to the hypothesis that, in addition to an abnormal contraction pattern of the circular muscle, an overall increased muscle thickness and an abnormal longitudinal muscle contraction could be added as pathophysiological factors. The increase in muscle thickness could be an important indicator of the severity of diseases, such as achalasia, distal esophageal spasm, or hypercontractile esophagus. More studies are required before definitive conclusions can be reached, but HFIUS employed simultaneously with HRM could provide a more complete and precise evaluation of these esophageal motor disorders.<\/jats:p>","DOI":"10.1111\/nyas.13313","type":"journal-article","created":{"date-parts":[[2017,1,31]],"date-time":"2017-01-31T17:04:27Z","timestamp":1485882267000},"page":"60-66","source":"Crossref","is-referenced-by-count":4,"title":["Catheter\u2010based high\u2010frequency intraluminal ultrasound imaging is a powerful tool to study esophageal dysmotility patients"],"prefix":"10.1111","volume":"1395","author":[{"given":"Cecilio","family":"Santander","sequence":"first","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Digestive Motility Unit, IIS\u2010IP and CIBEREHD, Universidad Aut\u00f3noma de Madrid Hospital Universitario de La Princesa (HULP)  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Perea","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Digestive Motility Unit, IIS\u2010IP and CIBEREHD, Universidad Aut\u00f3noma de Madrid Hospital Universitario de La Princesa (HULP)  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda","family":"Caldas","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Digestive Motility Unit, IIS\u2010IP and CIBEREHD, Universidad Aut\u00f3noma de Madrid Hospital Universitario de La Princesa (HULP)  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pere","family":"Clave","sequence":"additional","affiliation":[{"name":"Universitat Aut\u00f2noma de Barcelona Hospital de Matar\u00f3  Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,1,31]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"421","article-title":"Longitudinal muscle of the esophagus: its role in esophageal health and disease","volume":"29","author":"Mittal R.K.","year":"2013","journal-title":"Curr. 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