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Endoscopy, esophageal high\u2010resolution manometry (HRM), ambulatory pH or pH\u2010impedance manometry, and barium radiography are commonly used for esophageal function testing; functional lumen imaging probe is an emerging option. Recent consensus guidelines have provided direction in using test findings toward defining mechanisms of esophageal symptoms. The Chicago Classification describes hierarchical steps in diagnosing esophageal motility disorders. The Lyon Consensus characterizes conclusive evidence on esophageal testing for a diagnosis of gastroesophageal reflux disease (GERD), and establishes a motor classification of GERD. Taking these recent advances into consideration, our discussion focuses primarily on the indications, technique, equipment, and interpretation of esophageal HRM and ambulatory reflux monitoring in the evaluation of esophageal symptoms, and describes indications for alternative esophageal tests.<\/jats:p>","DOI":"10.1111\/nyas.13709","type":"journal-article","created":{"date-parts":[[2018,5,13]],"date-time":"2018-05-13T05:25:59Z","timestamp":1526189159000},"page":"239-253","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":46,"title":["Indications and interpretation of esophageal function testing"],"prefix":"10.1111","volume":"1434","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3388-0660","authenticated-orcid":false,"given":"C. 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