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Specifically, the so\u2010called cholinergic anti\u2010inflammatory pathway seems to play a key role in the homeostasis of the neuro\u2013immune\u2013endocrine axis by adjusting the vagus nerve activity during parturition. Here, we provide insights into the importance of the vagus during parturition from an autonomic, endocrine, and immune interplay perspective, and describe the potential role of heart rate variability analysis to explore these interactions noninvasively, economically, and accessibly.<\/jats:p>","DOI":"10.1111\/nyas.13860","type":"journal-article","created":{"date-parts":[[2018,5,29]],"date-time":"2018-05-29T05:51:58Z","timestamp":1527573118000},"page":"22-30","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Neuroautonomic activity evidences parturition as a complex and integrated neuro\u2013immune\u2013endocrine process"],"prefix":"10.1111","volume":"1437","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5361-5007","authenticated-orcid":false,"given":"Jos\u00e9 Javier","family":"Reyes\u2010Lagos","sequence":"first","affiliation":[{"name":"Faculty of Medicine Autonomous University of the State of Mexico (UAEMex)  Toluca Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia Ivette","family":"Ledesma\u2010Ram\u00edrez","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Autonomous University of the State of Mexico (UAEMex)  Toluca Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriana Cristina","family":"Pliego\u2010Carrillo","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Autonomous University of the State of Mexico (UAEMex)  Toluca Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel \u00c1ngel","family":"Pe\u00f1a\u2010Castillo","sequence":"additional","affiliation":[{"name":"Basic Sciences and Engineering Division, Campus Iztapalapa Metropolitan Autonomous University (UAM)  Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan Carlos","family":"Echeverr\u00eda","sequence":"additional","affiliation":[{"name":"Basic Sciences and Engineering Division, Campus Iztapalapa Metropolitan Autonomous University (UAM)  Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrique","family":"Becerril\u2010Villanueva","sequence":"additional","affiliation":[{"name":"Department of Psychoimmunology National Institute of Psychiatry (INP) Ramon de la Fuente  Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6067-6868","authenticated-orcid":false,"given":"Lenin","family":"Pav\u00f3n","sequence":"additional","affiliation":[{"name":"Department of Psychoimmunology National Institute of Psychiatry (INP) Ramon de la Fuente  Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3458-197X","authenticated-orcid":false,"given":"Gustavo","family":"Pacheco\u2010L\u00f3pez","sequence":"additional","affiliation":[{"name":"Biological and Health Sciences Division, Campus Lerma Metropolitan Autonomous University (UAM)  Lerma Mexico"},{"name":"Department of Health Sciences, and Technology Swiss Federal Institute of Technology (ETH) Zurich  Schwerzenbach Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,5,28]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"428","volume-title":"Recent Advances in Research on the Human Placenta","author":"Schjenken J.E.","year":"2012"},{"key":"e_1_2_7_3_1","first-page":"1875","volume-title":"Knobil and Neill's Physiology of Reproduction","author":"Plant T.M.","year":"2015"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2006.09.008"},{"key":"e_1_2_7_5_1","doi-asserted-by":"crossref","first-page":"111","DOI":"10.3233\/NIB-2011-020","article-title":"Reciprocal brain\u2013body neuro\u2013endocrine\u2013immune interactions: role in maintaining pregnancy","volume":"2","author":"Parker V.J.","year":"2011","journal-title":"Adv. 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