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It has been used primarily in esophageal diseases, in particular, in the assessment of achalasia, esophagogastric junction outflow obstruction, and eosinophilic esophagitis (EoE). The usage and publications have increased over the past decade and it is now an essential tool in the armamentarium of the esophagologist. Indications are emerging outside of the esophagus, in particular with regard to gastroparesis. Our paper will review the history of FLIP, optimal current usage, data for key esophageal disorders (including achalasia, reflux, and EoE), data for nonesophageal disorders, and our sense as to whether FLIP is ready for prime time, as well as gaps in evidence and suggestions for future research.<\/jats:p>","DOI":"10.1111\/nyas.14463","type":"journal-article","created":{"date-parts":[[2020,8,28]],"date-time":"2020-08-28T05:38:22Z","timestamp":1598593102000},"page":"16-25","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["The functional lumen imaging probe in gastrointestinal disorders: the past, present, and future"],"prefix":"10.1111","volume":"1482","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2625-1169","authenticated-orcid":false,"given":"John O.","family":"Clarke","sequence":"first","affiliation":[{"name":"Department of Medicine Stanford University  Redwood City 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