{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T20:30:38Z","timestamp":1792269038215,"version":"4.4.0"},"reference-count":11,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,12,31]],"date-time":"2020-12-31T00:00:00Z","timestamp":1609372800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["nyaspubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Annals of the New York Academy of Sciences"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In this article, we report the different presentations of thiamine deficiency disorders seen at a remote rural mission hospital in Northeast India, including investigations, treatment, and recovery. Two case studies, one of an infant with cardiac beriberi and the other of a nonalcoholic adult presenting with peripheral neuropathy, cardiomyopathy, and metabolic acidosis and responding to thiamine supplementation, are described in detail. We share our experience with these clinical entities over the past two decades, including recent research and lessons learned, and suggest ways forward to identify at\u2010risk populations in Northeast India, improve early diagnosis and treatment, and promote preventive public health strategies.<\/jats:p>","DOI":"10.1111\/nyas.14552","type":"journal-article","created":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T12:26:45Z","timestamp":1609504005000},"page":"96-107","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["The rediscovery of thiamine deficiency disorders at a secondary level mission hospital in Northeast India"],"prefix":"10.1111","volume":"1498","author":[{"given":"Roshine Mary","family":"Koshy","sequence":"first","affiliation":[{"name":"Department of Medicine Makunda Christian Leprosy and General Hospital Assam India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shajin","family":"Thankaraj","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Makunda Christian Leprosy and General Hospital Assam India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay Anand","family":"Ismavel","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Makunda Christian Leprosy and General Hospital Assam India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolin V.","family":"Solomi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Makunda Christian Leprosy and General Hospital Assam India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,12,31]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.15566\/cjgh.v7i2.389"},{"key":"e_1_2_7_3_1","unstructured":"WHO.1999.Thiamine deficiency and its prevention and control in major emergencies. WHO\/NHD\/99.13."},{"key":"e_1_2_7_4_1","doi-asserted-by":"crossref","first-page":"178","DOI":"10.4103\/cjhr.cjhr_33_18","article-title":"Suspected thiamine deficiency presenting as peripheral neuropathy among peripartum women in a hospital in rural Assam: a neglected public health problem","volume":"5","author":"Koshy R.M.","year":"2018","journal-title":"CHRSIMED J. Health Res"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13312-020-1969-5"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.4103\/1319-2442.248314"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A4756"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0025727300004622"},{"key":"e_1_2_7_9_1","first-page":"1","article-title":"The problem of epidemic dropsy and beriberi","volume":"60","author":"Hugh W.A.","year":"1925","journal-title":"Indian Med. 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Last accessed November 11 2020.https:\/\/tatanin.org\/#\/dashboard\/nutrient-intake."},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13312-020-1800-3"}],"container-title":["Annals of the New York Academy of Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nyas.14552","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/nyas.14552","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/nyaspubs.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/nyas.14552","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,20]],"date-time":"2024-08-20T14:35:29Z","timestamp":1724164529000},"score":1,"resource":{"primary":{"URL":"https:\/\/nyaspubs.onlinelibrary.wiley.com\/doi\/10.1111\/nyas.14552"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,31]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["10.1111\/nyas.14552"],"URL":"https:\/\/doi.org\/10.1111\/nyas.14552","archive":["Portico"],"relation":{},"ISSN":["0077-8923","1749-6632"],"issn-type":[{"value":"0077-8923","type":"print"},{"value":"1749-6632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,31]]},"assertion":[{"value":"2020-10-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-31","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}