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Characterizing the presence of autonomic dysfunction in concussed persons is inconsistent and conventional metrics of autonomic function cannot differentiate the presence\/absence of injury. Mayer wave (MW) activity originates through baroreflex adjustments to blood pressure (BP) oscillations that appear in the low\u2010frequency (LF: 0.04\u20130.15 Hz) band of the BP and heart rate (HR) power spectrum after a fast Fourier transform. We prospectively explored MW activity (\u223c0.1 Hz) in 19 concussed and 19 noninjured athletes for 5 min while seated at rest within 48 h and 1 week of injury. MW activity was derived from the LF band of continuous digital electrocardiogram and beat\u2010to\u2010beat BP signals (LFHR, LF\u2010SBP, MWHR, and MW\u2010SBP, respectively); a proportion between MWBP and MWHR was computed (cMW). At 48 h, the concussion group had a significantly lower MWBP and cMW than controls; these differences were gone by 1 week. MWHR, LFHR, and LF\u2010SBP were not different between groups at either visit. Attenuated sympathetic vasomotor tone was present and the central autonomic mechanisms regulating MW activity to the heart and peripheral vasculature became transiently discordant early after concussion with apparent resolution by 1 week.<\/jats:p>","DOI":"10.1111\/nyas.14683","type":"journal-article","created":{"date-parts":[[2021,9,4]],"date-time":"2021-09-04T05:20:35Z","timestamp":1630732835000},"page":"121-132","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Use of Mayer wave activity to demonstrate aberrant cardiovascular autonomic control following sports concussion injury"],"prefix":"10.1111","volume":"1507","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1376-5152","authenticated-orcid":false,"given":"Michael F.","family":"La Fountaine","sequence":"first","affiliation":[{"name":"Department of Physical Therapy, School of Health and Medical Sciences Seton Hall University Nutley New Jersey"},{"name":"Department of Medical Sciences Hackensack Meridian School of Medicine Nutley New Jersey"},{"name":"Department of Neurology Hackensack Meridian School of Medicine Nutley New Jersey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asante N.","family":"Hohn","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, School of Health and Medical Sciences Seton Hall University Nutley New Jersey"},{"name":"Spectrum Physical Therapy and Athletic Training Morristown New Jersey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline L.","family":"Leahy","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, School of Health and Medical Sciences Seton Hall University Nutley New Jersey"},{"name":"SportsCare Physical Therapy Cedar Knolls New Jersey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony J.","family":"Testa","sequence":"additional","affiliation":[{"name":"Center for Sports Medicine Seton Hall University South Orange New Jersey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0684-2930","authenticated-orcid":false,"given":"Joseph P.","family":"Weir","sequence":"additional","affiliation":[{"name":"Department of Health, Sport and Exercise Sciences University of Kansas Lawrence Kansas"},{"name":"Osness Human Performance Laboratories University of Kansas Lawrence Kansas"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,9,3]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000335246.93495.92"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.1976.56.1.100"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.1952.tb00889.x"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.1952.tb00890.x"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(95)00426-2"},{"key":"e_1_2_10_7_1","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1093\/oso\/9780195051063.003.0009","volume-title":"Central Regulation of Autonomic Functions","author":"Guyenet P.G.","year":"1990"},{"key":"e_1_2_10_8_1","volume-title":"Primer on the Autonomic Nervous System","author":"Robertson D.","year":"2012"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2001.tb03662.x"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/cpf.12487"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.3109\/02699052.2015.1093659"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpsycho.2017.11.016"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2016.00013"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/JSM.0000000000000183"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00499.2016"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0000000000001833"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/02699052.2016.1226385"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2014.01.095"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.4085\/1062-6050-46.3.230"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.4085\/1062-6050-0578.19"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2020.547126"},{"key":"e_1_2_10_22_1","first-page":"281","article-title":"Studien zur physiologie des herzes und der blutgefasse","volume":"74","author":"Mayer S.","year":"1876","journal-title":"Sitz. 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