{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T19:19:21Z","timestamp":1777749561806,"version":"3.51.4"},"reference-count":45,"publisher":"Wiley","license":[{"start":{"date-parts":[[2024,9,23]],"date-time":"2024-09-23T00:00:00Z","timestamp":1727049600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["nyaspubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Annals of the New York Academy of Sciences"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Artificial intelligence (AI) and psychedelic medicines are among the most high\u2010profile evolving disruptive innovations within mental healthcare in recent years. Although AI and psychedelics may not have historically shared any common ground, there exists the potential for these subjects to combine in generating innovative mental health treatment approaches. In order to inform our perspective, we conducted a scoping review of relevant literature up to late August 2024 via PubMed intersecting AI with psychomedical use of psychedelics. Our perspective covers the potential application of AI in psychedelic medicine for: drug discovery and clinical trial optimization (including pharmacodynamics); study design; understanding psychedelic experiences; personalization of treatments; clinical screening, delivery, and follow\u2010up (potentially delivered via chatbots\/apps); application of psychological preparation, integration, and general mental health support; its role in enhancing treatment via brain modulatory devices (including virtual reality and haptic suits); and the consideration of ethical and security safeguards. Challenges include the need for sufficient data protection and security, and a range of necessary ethical protections. Future avenues of exploration could involve directly administering psychedelics (or providing algorithm\u2010generated effects) to inorganic AI\u2010interfaced neural networks that may exceed human brain activity (i.e., cognitive capacity) and intelligence.<\/jats:p>","DOI":"10.1111\/nyas.15229","type":"journal-article","created":{"date-parts":[[2024,9,23]],"date-time":"2024-09-23T05:28:28Z","timestamp":1727069308000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Artificial intelligence and psychedelic medicine"],"prefix":"10.1111","author":[{"given":"Jerome","family":"Sarris","sequence":"first","affiliation":[{"name":"The Florey Institute of Neuroscience and Mental Health Melbourne University  Melbourne Victoria Australia"},{"name":"Psychae Institute  Melbourne Victoria Australia"},{"name":"Centre for Mental Health Swinburne University  Melbourne Victoria Australia"},{"name":"NICM Health Research Institute Western Sydney University  Westmead New South Wales Australia"},{"name":"Psychae Therapeutics  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Halman","sequence":"additional","affiliation":[{"name":"Psychae Therapeutics  Melbourne Victoria Australia"},{"name":"School of Population and Global Health Melbourne University  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Urokohara","sequence":"additional","affiliation":[{"name":"The Florey Institute of Neuroscience and Mental Health Melbourne University  Melbourne Victoria Australia"},{"name":"Psychae Therapeutics  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathew","family":"Lehrner","sequence":"additional","affiliation":[{"name":"Psychae Therapeutics  Melbourne Victoria Australia"},{"name":"The Ritchie Centre, Hudson Institute of Medical Research  Clayton Victoria Australia"},{"name":"Department of Obstetrics and Gynaecology Monash University  Clayton Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Perkins","sequence":"additional","affiliation":[{"name":"Psychae Institute  Melbourne Victoria Australia"},{"name":"Centre for Mental Health Swinburne University  Melbourne Victoria Australia"},{"name":"Psychae Therapeutics  Melbourne Victoria Australia"},{"name":"School of Population and Global Health Melbourne University  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,9,23]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.14764"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsmedchemlett.3c00333"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2020.10.010"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41592\u2010020\u201001004\u20103"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213\u2010023\u201006432\u20105"},{"key":"e_1_2_9_7_1","doi-asserted-by":"crossref","unstructured":"Selbst A. Boyd D. Friedler S. Venkatasubramanian S. &Vertesi J.(2019).Fairness and abstraction in sociotechnical systems. 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