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However, the relationship between the functional connectivity (FC) in these regions and the music perception ability of amusia in tonal language speakers remains unclear. In this study, we investigated the FC characteristics of amusia in Mandarin speakers in resting\u2010state functional magnetic resonance imaging data by voxel\u2010wise connectivity analyses with seeds in left and right Heschl's gyri (HG) and region of interest (ROI)\u2010to\u2010ROI connectivity analyses. Our findings indicate increased connectivity between right HG and bilateral posterior superior temporal gyrus, as determined by voxel\u2010wise connectivity analyses in amusia. Conversely, reduced connectivity was observed between bilateral HG and bilateral IFG (orbital part) as assessed through ROI\u2010to\u2010ROI connectivity analyses in amusia when compared to controls. Moreover, the music perception scores of amusia in Mandarin speakers were associated with diminished connectivity between the left HG and the right IFG. This study furnishes direct evidence for the link between music perception deficits and the aberrant frontotemporal connectivity of congenital amusia in tonal language speakers in resting state.<\/jats:p>","DOI":"10.1111\/nyas.15247","type":"journal-article","created":{"date-parts":[[2024,10,30]],"date-time":"2024-10-30T12:44:32Z","timestamp":1730292272000},"page":"140-150","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Altered resting\u2010state connectivity of the auditory cortex in congenital amusia: A functional magnetic resonance imaging study in Mandarin speakers"],"prefix":"10.1111","volume":"1541","author":[{"given":"Zhishuai","family":"Jin","sequence":"first","affiliation":[{"name":"Medical Psychological Center The Second Xiangya Hospital, Central South University Changsha Hunan China"},{"name":"Faculty of Education Henan Normal University Xinxiang Henan 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