{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T16:28:31Z","timestamp":1778084911132,"version":"3.51.4"},"reference-count":186,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T00:00:00Z","timestamp":1740700800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T00:00:00Z","timestamp":1740700800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["nyaspubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ann NY Acad Sci"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Human regulatory systems largely evolved under conditions of food and information scarcity but are now being forced to deal with abundance. The impact of abundance and the inability of human regulatory systems to adapt to it have fed a surge in dual health challenges: (1) a rise in obesity related to food abundance and (2) a rise in stress and anxiety related to information abundance. No single framework has been developed to describe why and how the transition from scarcity to abundance has been so challenging. Here, we provide a speculative model based on predictive processing. We suggest that whereas scarcity (above destructive lower bounds like famine or information voids) preserves the fidelity of the relationship between prediction errors and predictions, abundance distorts this relationship. Furthermore, prediction error minimization is enhanced under scarcity (as the number of competing states in the niche is restricted), whereas the opposite is true under abundance. We also discuss how abundance warps the fundamental drive for seeking novelty by fueling the brain's exploration (as opposed to exploitation) mode. Ameliorative strategies for regulating food and information abundance may largely depend on simulating scarcity, that environmental condition to which human regulatory systems have adapted over millennia.<\/jats:p>","DOI":"10.1111\/nyas.15302","type":"journal-article","created":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T01:27:26Z","timestamp":1741742846000},"page":"16-27","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Human regulatory systems in the age of abundance: A predictive processing perspective"],"prefix":"10.1111","volume":"1545","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5483-4452","authenticated-orcid":false,"given":"Otto","family":"Muzik","sequence":"first","affiliation":[{"name":"Department of Pediatrics Wayne State University School of Medicine  Detroit Michigan USA"},{"name":"Department of Radiology Wayne State University School of Medicine  Detroit Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vaibhav A.","family":"Diwadkar","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Neurosciences Wayne State University School of Medicine  Detroit Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,2,28]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0029665107005344"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.2471\/BLT.14.150565"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2009.28595"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1089\/154099903321576565"},{"key":"e_1_2_14_6_1","volume-title":"Data smog: Surviving the information glut","author":"Shenk D.","year":"1998"},{"key":"e_1_2_14_7_1","first-page":"49","article-title":"Information overload: Causes, consequences and remedies\u2010A study","volume":"15","author":"Hoq K. 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