{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T19:44:51Z","timestamp":1789847091718,"version":"4.0.1"},"reference-count":48,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T00:00:00Z","timestamp":1776729600000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["nyaspubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ann NY Acad Sci"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Feline leukemia virus (\n                    <jats:italic>Gammaretrovirus felleu<\/jats:italic>\n                    ) causes variable pathologies, partially modulated by its endogenous form (enFeLV). Although enFeLV is found in genomes of all species of the\n                    <jats:italic>Felis<\/jats:italic>\n                    genus, the limitations of transposable element sequencing have hindered a comprehensive characterization. In this study, we examined 17 felid genomes for enFeLV copies, confirming that enFeLV is restricted to the\n                    <jats:italic>Felis<\/jats:italic>\n                    genus. From the long\u2010read genomes of\n                    <jats:italic>Felis catus<\/jats:italic>\n                    ,\n                    <jats:italic>Felis nigripes<\/jats:italic>\n                    , and\n                    <jats:italic>Felis chaus<\/jats:italic>\n                    , we identified 73 solo LTRs, 64 copies with genic segments, and 4 atypical copies. These were annotated and characterized using recombination assessment, phylogenetic analysis, insertion dating, and Fisher's exact tests. All enFeLV copies shared a single origin, with insertions occurring within the last 3.5 million years, except for predicted recombinants. Copy distribution, dating, and the phylogenetic position of\n                    <jats:italic>F. chaus<\/jats:italic>\n                    copies reinforce the hypothesis of a recent introgression of enFeLV into this species. Furthermore, 41 copies exhibit identical LTR pairs and 14 retain intact open reading frames spanning the viral genome. Uneven evolutionary pressures across the enFeLV genome were evidenced by discrepancies between tree topologies of individual genes and the preferential loss of\n                    <jats:italic>pol<\/jats:italic>\n                    . We conclude that enFeLV has undergone a complex post\u2010endogenization evolutionary history and urge additional studies of other endogenous retroviruses.\n                  <\/jats:p>","DOI":"10.1111\/nyas.70278","type":"journal-article","created":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T18:16:51Z","timestamp":1776795411000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Evolutionary Dynamics of Endogenous Feline Leukemia Virus in the\n                    <i>Felis<\/i>\n                    Genus Through the Lens of Genomics"],"prefix":"10.1111","volume":"1558","author":[{"given":"Ricardo","family":"Mouta","sequence":"first","affiliation":[{"name":"Department of Genetics and Graduate Program in Genetics Universidade Federal do Rio de Janeiro \u2010 UFRJ  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liliane Tavares de Faria","family":"Cavalcante","sequence":"additional","affiliation":[{"name":"Department of Genetics and Graduate Program in Genetics Universidade Federal do Rio de Janeiro \u2010 UFRJ  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo Alves","family":"Soares","sequence":"additional","affiliation":[{"name":"Department of Genetics and Graduate Program in Genetics Universidade Federal do Rio de Janeiro \u2010 UFRJ  Rio de Janeiro Brazil"},{"name":"Oncovirology Program Brazilian National Cancer Institute \u2010 INCA  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos G.","family":"Schrago","sequence":"additional","affiliation":[{"name":"Department of Genetics and Graduate Program in Genetics Universidade Federal do Rio de Janeiro \u2010 UFRJ  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirela","family":"D'arc","sequence":"additional","affiliation":[{"name":"Department of Genetics and Graduate Program in Genetics Universidade Federal do Rio de Janeiro \u2010 UFRJ  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filipe Romero Rabelo","family":"Moreira","sequence":"additional","affiliation":[{"name":"Department of Genetics and Graduate Program in Genetics Universidade Federal do Rio de Janeiro \u2010 UFRJ  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9 Felipe","family":"Andrade dos Santos","sequence":"additional","affiliation":[{"name":"Department of Genetics and Graduate Program in Genetics Universidade Federal do Rio de Janeiro \u2010 UFRJ  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,21]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/202567a0"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0004744"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2501.181347"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.7589\/0090\u20103558\u201035.1.121"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.7589\/0090-3558-35.4.678"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.7589\/0090\u20103558\u201039.3.696"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.52892"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2010.06.010"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1128\/9781555819217.ch47"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.58.3.825-834.1986"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.68.4.2151-2160.1994"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev\u2010animal\u2010050620"},{"key":"e_1_2_10_14_1","unstructured":"A.Kitchener C.Breitenmoser E.Eizirik A.Gentry L.Werdelin A.Wilting et\u00a0al.A Revised Taxonomy of the Felidae. 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