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This evidence suggests that loneliness is not simply an issue in HICs or a result of living alone. Instead, loneliness is closely tied to structural factors, some of which may be more salient in LMICs. In this perspective article, the contextual aspects that are closely tied to loneliness in research from LMICs, where the majority of the world's population resides, are presented. The discussed aspects go beyond the differentiation between individualism versus collectivism found in loneliness literature from HICs. Instead, the article sheds light on the often\u2010cyclical relationships between loneliness and poverty, political instability, stigma, migration, culture, religion, and climate change. Shedding light on loneliness research from LMICs, this perspective provides novel and exciting directions for loneliness research in both HICs and LMICs. As these structural influences are often entangled and mostly affect those populations who are already socially and economically disadvantaged, this perspective echoes scholars who view loneliness as a social justice issue and, additionally, calls for recognizing loneliness as a truly global phenomenon.<\/jats:p>","DOI":"10.1111\/nyas.70315","type":"journal-article","created":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T22:03:04Z","timestamp":1780437784000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Reframing Loneliness as a Global Phenomenon: Insights From the Majority World"],"prefix":"10.1111","volume":"1560","author":[{"given":"Samia C.","family":"Akhter\u2010Khan","sequence":"first","affiliation":[{"name":"Department of Global Health &amp; Social Medicine King's College London  London UK"},{"name":"Research Group \u201cClimate, Aging and Relationships (CARE)\u201d, Center for Health Services Research Brandenburg Medical School R\u00fcdersdorf Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,2]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/1683478X.2022.2115623"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj\u20102021\u2010067068"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2023.116438"},{"key":"e_1_2_15_5_1","volume-title":"From Loneliness to Social Connection\u2014Charting a Path to Healthier Societies: Report of the WHO Commission on Social Connection [Internet]","author":"World Health Organization","year":"2025"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022022113509881"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/00223980.2011.631612"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010025\u201056764\u20103"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healthpol.2025.105553"},{"key":"e_1_2_15_10_1","volume-title":"Our Epidemic of Loneliness and Isolation: The U.S. Surgeon General's Advisory on the Healing Effects of Social Connection and Community [Internet]","author":"Office of the U.S. Surgeon General","year":"2023"},{"key":"e_1_2_15_11_1","unstructured":"L.Heu \u201cIs Loneliness Just a Problem in Individualistic Cultures?\u201dPsychology Today [Internet]2023 accessed May 5 2025 https:\/\/www.psychologytoday.com\/us\/blog\/lonely\u2010not\u2010alone\/202309\/is\u2010loneliness\u2010just\u2010a\u2010problem\u2010in\u2010individualistic\u2010cultures\u20102."},{"key":"e_1_2_15_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(23)01411\u20103"},{"key":"e_1_2_15_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjgh\u20102022\u2010009704"},{"key":"e_1_2_15_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/pops.12965"},{"key":"e_1_2_15_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/14647001211062739"},{"key":"e_1_2_15_16_1","unstructured":"World Bank \u201cWorld Bank Country and Lending Groups [Internet] \u201d2025 accessed Oct 20 2025 https:\/\/datahelpdesk.worldbank.org\/knowledgebase\/articles\/906519\u2010world\u2010bank\u2010country\u2010and\u2010lending\u2010groups."},{"key":"e_1_2_15_17_1","unstructured":"B. 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