{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T19:20:07Z","timestamp":1791487207464,"version":"4.3.4"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T00:00:00Z","timestamp":1781654400000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["nyaspubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ann NY Acad Sci"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Micronutrient deficiencies remain widespread across sub\u2010Saharan Africa, reflecting not only inadequate diets but also limitations in how current interventions are designed and delivered. Universal salt iodization (USI) has achieved broad population coverage and represents one of the most successful large\u2010scale nutrition interventions globally. However, most fortification strategies continue to target single nutrients in isolation, missing opportunities to address overlapping deficiencies. Recent evidence from Ethiopia demonstrates that folic acid can be co\u2010fortified with iodized salt without compromising iodine status, offering proof\u2010of\u2010concept that existing platforms can be leveraged for integrated micronutrient delivery. This perspective argues that integrated fortification strategies combining iodine, folic acid, and potentially other micronutrients into widely consumed vehicles offer a more efficient, scalable, and equitable pathway to improve population\u2010level nutritional status. However, translating proof\u2010of\u2010concept into public health impact requires addressing key challenges: biological effectiveness, product stability, implementation feasibility, quality assurance, and population heterogeneity. We propose a policy agenda that includes regulatory reform, investment in surveillance systems, and coordinated action across health, trade, and food safety sectors. Integrated fortification should complement, not replace, broader strategies like dietary diversification and supplementation, while offering a pragmatic pathway to address overlapping micronutrient deficiencies at scale across Africa and other low\u2010 and middle\u2010income settings.<\/jats:p>","DOI":"10.1111\/nyas.70334","type":"journal-article","created":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T19:14:53Z","timestamp":1781723693000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Leveraging Salt Fortification Platforms to Address Multiple\u2010Micronutrient Deficiencies in Africa: A Policy Opportunity"],"prefix":"10.1111","volume":"1560","author":[{"given":"Taddese","family":"Zerfu","sequence":"first","affiliation":[{"name":"International Food Policy Research Institute (IFPRI)  Addis Ababa Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amare Abera","family":"Tareke","sequence":"additional","affiliation":[{"name":"Biomedical Science Education and Service Directorate College of Medicine and Health Sciences Wollo University  Dessie Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dawit Alemayehu","family":"Chekol","sequence":"additional","affiliation":[{"name":"Ethiopian Public Health Institute (EPHI)  Addis Ababa Ethiopia"},{"name":"University of Galway  Galway Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,17]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.13963"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.13548"},{"issue":"15","key":"e_1_2_6_4_1","first-page":"421","article-title":"Optimal Serum and Red Blood Cell Folate Concentrations in Women of Reproductive Age for Prevention of Neural Tube Defects: World Health Organization Guidelines","volume":"64","author":"Cordero A. M.","year":"2015","journal-title":"MMWR Morbidity and Mortality Weekly Report"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2023.102366"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hnm.2025.200335"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0318422"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2019.0719"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1530\/EJE\u201021\u20100171"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajcnut.2026.101204"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102621.2003.tb07031.x"},{"key":"e_1_2_6_12_1","unstructured":"Y. K.Chan (University of Toronto 2025) PhD diss."},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.advnut.2025.100567"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/advances\/nmy008"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41430\u2010026\u201001761\u2010y"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajcnut.2025.04.009"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.2147\/NDS.S412893"},{"key":"e_1_2_6_18_1","unstructured":"Nutrition International\/EPHI Government of Ethiopia Nutrition International and Partners Introduce Double\u2010Fortified Salt to Reduce Neural Tube Defects in Ethiopia(Nutrition International\/EPHI 2026)."},{"key":"e_1_2_6_19_1","volume-title":"Micronutrient Premix Granules: Characterization, Failure Analysis, and Application in Fortified Bouillon Cubes","author":"Chan Y. 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