{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T13:06:51Z","timestamp":1789218411562,"version":"build-2803163510"},"reference-count":43,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100019718","name":"Stiftung Max und Sophiel\u00e8ne Iten-Kohaut","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100019718","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["nyaspubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ann NY Acad Sci"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Persistent postural\u2010perceptual dizziness (PPPD) patients with visual dependency rely more on visual cues and may have altered oculomotor responses to visual motion. This study examined early eye movement responses to large\u2010field motion stimuli\u2014the ocular following responses (OFRs)\u2014in 30 PPPD patients and 29 healthy controls. Participants viewed horizontal motion in peripheral and\/or central visual fields while eye movements were recorded. OFR velocity 200\u00a0ms after stimulus onset and suppression efficacy were analyzed across four central field sizes from 5\u00b0 to 42\u00b0 radius. Both groups exhibited strong OFRs to stimuli in the central visual field that increased with the size of the stimulation area. When the central visual field was stationary and the surrounding area moved, patients showed significantly higher eye velocity than controls. Both groups could partially suppress OFRs, but healthy controls were more effective at suppressing eye movements during peripheral stimulation. Patients also showed greater visual dependency on the dynamic subjective visual vertical (2.2\u00b0 vs. 1.2\u00b0), which correlated with OFR magnitude. Overall, PPPD patients were less able to keep their eyes still during peripheral visual motion, producing greater retinal slip and disrupting volitional fixation\u2014an abnormality that may contribute to dizziness and discomfort in visually complex environments.<\/jats:p>","DOI":"10.1111\/nyas.70378","type":"journal-article","created":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T16:36:05Z","timestamp":1786552565000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Early Ocular Response to Visual Motion in Patients With Persistent Postural\u2010Perceptual Dizziness"],"prefix":"10.1111","volume":"1562","author":[{"given":"Vergil V.","family":"Mavrodiev","sequence":"first","affiliation":[{"name":"Department of Neurology University Hospital Zurich  Zurich Switzerland"},{"name":"Department of Ophthalmology University Hospital Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konrad P.","family":"Weber","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospital Zurich  Zurich Switzerland"},{"name":"Department of Ophthalmology University Hospital Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher J.","family":"Bockisch","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospital Zurich  Zurich Switzerland"},{"name":"Department of Ophthalmology University Hospital Zurich  Zurich Switzerland"},{"name":"Department of Otorhinolaryngology University Hospital Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabienne C.","family":"Fierz","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology University Hospital Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,12]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"crossref","unstructured":"P.Kreyenmeier R.Kumbhani J. 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