{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T16:54:10Z","timestamp":1791305650271,"version":"4.3.1"},"reference-count":78,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:00:00Z","timestamp":1791244800000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["nyaspubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ann NY Acad Sci"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Supercooled liquids with negative Clapeyron slopes are more stable at constant volume than at constant pressure. We compare the isochoric and isobaric driving forces for incipient solidification via a first\u2010order perturbation expansion of the thermodynamic potentials in the solid mass fraction. The analysis yields a geometry\u2010independent inequality: the isochoric Helmholtz driving force is strictly smaller than the isobaric Gibbs driving force. It also introduces a dimensionless stability number\n                    <jats:italic>\u03a0<\/jats:italic>\n                    <jats:sub>0<\/jats:sub>\n                    \u00a0=\u00a0, where  and  are the solid and liquid specific volumes,  is the latent heat of fusion, and\n                    <jats:italic>\u03ba<\/jats:italic>\n                    <jats:sub>l<\/jats:sub>\n                    is the liquid isothermal compressibility.  ranks materials and guides supercooling design for negative\u2010Clapeyron\u2010slope substances. For water, \u00a0\u2248\u00a00.048. Cryoprotectants increase it several\u2010fold, suppressing nucleation beyond colligative freezing\u2010point depression.\n                  <\/jats:p>","DOI":"10.1111\/nyas.70417","type":"journal-article","created":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T16:10:25Z","timestamp":1791303025000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Thermodynamic Analysis of Enhanced Metastability in Isochoric Supercooled Liquids"],"prefix":"10.1111","volume":"1564","author":[{"given":"Boris","family":"Rubinsky","sequence":"first","affiliation":[{"name":"Department of Mechanical Engineering University of California, Berkeley  Berkeley California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,6]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cryobiol.2004.12.002"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.3889"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000499453"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.3389\/frtra.2023.1269706"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2025.1631214"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cryobiol.2026.105680"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s42003\u2010021\u201002650\u20109"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2025.1566080"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408398.2023.2248515"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0069334"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010018\u201005636\u20100"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3588"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10068\u2010020\u201000750\u20106"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.5187\/jast.2023.e65"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2026.148116"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006\u20103495(95)80389\u20109"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/md15020027"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1063\/1.5145334"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1088\/1873\u20104030\/ae2ec2"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.2139\/ssrn.4432713"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1063\/5.0051662"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1063\/5.0155494"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cryobiol.2022.03.003"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrep.2023.101485"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.3390\/bioengineering10080934"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.postharvbio.2022.112072"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cryobiol.2006.04.001"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/s42005\u2010020\u20100303\u20109"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.5b00744"},{"key":"e_1_2_11_31_1","volume-title":"Nucleation in Condensed Matter: Applications in Materials and Biology","author":"Kelton K. 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