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Obesity during the past few decades was paralleled with several changes in dietary habits favouring low phosphorus consumption. This is believed to compromise adenosine triphosphate (<jats:styled-content style=\"fixed-case\">ATP<\/jats:styled-content>) production that is involved in the regulation of energy metabolism. Ingestion of high\u2010carbohydrate\u2013low phosphorus food is known to increase insulin release, to simultaneously stimulate peripheral uptake of phosphorus and the phosphorylation of many compounds. This creates a competition for phosphorus that compromises its availability for <jats:styled-content style=\"fixed-case\">ATP<\/jats:styled-content> production, possibly translated into low diet\u2010induced thermogenesis. Moreover, reduced hepatic <jats:styled-content style=\"fixed-case\">ATP<\/jats:styled-content> production is believed to be transmitted through neural afferents to the central nervous system, resulting in an increase in food intake. On the other hand, the positive relation between phosphorus and red blood cell 2,3\u2010diphosphoglycerate, which reduces oxygen affinity to haemoglobin, would be expected to reduce the capacity for physical activity. In line with that, plasma phosphorus status was reported to be inversely related to body weight. Adequate intakes of phosphorus are thus potentially protective against rising obesity epidemic across the globe.<\/jats:p>","DOI":"10.1111\/obr.12039","type":"journal-article","created":{"date-parts":[[2013,5,16]],"date-time":"2013-05-16T10:28:39Z","timestamp":1368700119000},"page":"659-664","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Low phosphorus status might contribute to the onset of obesity"],"prefix":"10.1111","volume":"14","author":[{"given":"O. 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