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Although <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> patients diagnosed with bone loss may be asymptomatic, some suffer bone pains and have increased incidence of fractures. Adolescents with <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> are prone to increased prevalence of stress fractures, kyphoscoliosis and height loss.<\/jats:p><jats:p>The clinical picture of the various <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content>s involves endocrinopathies that contribute to impaired bone health.<\/jats:p><jats:p>Anorexia nervosa (<jats:styled-content style=\"fixed-case\">AN<\/jats:styled-content>) is characterized by low bone turnover, with relatively higher osteoclastic (bone resorptive) than osteoblastic (bone formation) activity. Bone loss in <jats:styled-content style=\"fixed-case\">AN<\/jats:styled-content> occurs in both the trabecular and cortical bones, although the former is more vulnerable.<\/jats:p><jats:p>Bone loss in <jats:styled-content style=\"fixed-case\">AN<\/jats:styled-content> has been shown to be influenced by malnutrition and low weight, reduced fat mass, oestrogen and androgen deficiency, glucocorticoid excess, impaired growth hormone\u2013insulin\u2010like growth factor 1 axis, and more.<\/jats:p><jats:p>Bone loss in <jats:styled-content style=\"fixed-case\">AN<\/jats:styled-content> may not be completely reversible despite recovery from the illness. Treatment modalities involving hormonal therapies have limited effectiveness, whereas increased caloric intake, weight gain and resumption of menses are essential to improved <jats:styled-content style=\"fixed-case\">BMD<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/obr.12117","type":"journal-article","created":{"date-parts":[[2013,10,25]],"date-time":"2013-10-25T16:19:32Z","timestamp":1382717972000},"page":"215-223","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Bone health in eating disorders"],"prefix":"10.1111","volume":"15","author":[{"given":"N.","family":"Zuckerman\u2010Levin","sequence":"first","affiliation":[{"name":"Eating Disorders Clinic Psychiatric Division Rambam Medical Center  Haifa Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z.","family":"Hochberg","sequence":"additional","affiliation":[{"name":"Pediatric Endocrinology Meyer Children's Hospital Rambam Medical 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