{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T17:48:33Z","timestamp":1792000113097,"version":"4.4.0"},"reference-count":98,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,1,4]],"date-time":"2019-01-04T00:00:00Z","timestamp":1546560000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Spanish Ministry of Education, Culture and Sport","award":["FPU16\/01093"],"award-info":[{"award-number":["FPU16\/01093"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity Reviews"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    Lifestyle interventions addressing diet, exercise\u2010training, sleep hygiene, and\/or tobacco\/alcohol cessation are recommended in the management of obstructive sleep apnoea (OSA). Yet their effectiveness on this condition still requires further research. This systematic review and meta\u2010analysis was aimed at establishing (a) the effectiveness of lifestyle interventions on apnoea\u2010hypopnoea index (AHI), oxygen desaturation index (ODI), excessive daytime sleepiness (EDS), and secondary OSA measures among adults, and (b) which intervention characteristics may drive the greatest improvements. A systematic search of studies was conducted using CINAHL, ProQuest, Psicodoc, Scopus, and Web of Science, from inception to April 2018. Standardized mean differences were calculated using the inverse variance method and random\u2010effects models. The meta\u2010analyses of 13 randomized controlled trials and 22 uncontrolled before\u2010and\u2010after studies (1420 participants) revealed significant reductions on AHI (\n                    <jats:italic>d<\/jats:italic>\n                    \u00a0=\u00a0\u22120.61 and \u22120.46, respectively), ODI (\n                    <jats:italic>d<\/jats:italic>\n                    \u00a0=\u00a0\u22120.61 and \u22120.46) and EDS (\n                    <jats:italic>d<\/jats:italic>\n                    \u00a0=\u00a0\u22120.41 and \u22120.49). Secondary OSA outcomes were also improved after interventions. However, effectiveness of interventions differed depending on their components, OSA severity, and gender. Thus, until future research further supports the differential effectiveness among lifestyle interventions on OSA, those addressing weight loss through diet and exercise\u2010training may be the most effective treatments for male patients with moderate\u2010severe OSA.\n                  <\/jats:p>","DOI":"10.1111\/obr.12824","type":"journal-article","created":{"date-parts":[[2019,1,4]],"date-time":"2019-01-04T17:59:07Z","timestamp":1546624747000},"page":"750-762","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":132,"title":["Weight loss and lifestyle interventions for obstructive sleep apnoea in adults: Systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3879-6468","authenticated-orcid":false,"given":"Almudena","family":"Carneiro\u2010Barrera","sequence":"first","affiliation":[{"name":"Mind, Brain, and Behaviour Research Centre, CIMCYC University of Granada  Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amparo","family":"D\u00edaz\u2010Rom\u00e1n","sequence":"additional","affiliation":[{"name":"Mind, Brain, and Behaviour Research Centre, CIMCYC University of Granada  Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro","family":"Guill\u00e9n\u2010Riquelme","sequence":"additional","affiliation":[{"name":"Mind, Brain, and Behaviour Research Centre, CIMCYC University of Granada  Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gualberto","family":"Buela\u2010Casal","sequence":"additional","affiliation":[{"name":"Mind, Brain, and Behaviour Research Centre, CIMCYC University of Granada  Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,1,4]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.27497"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/resp.12984"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.6878"},{"key":"e_1_2_8_5_1","first-page":"601","article-title":"Obstructive sleep apnea syndrome effects on quality of life and daytime sleepiness","volume":"12","author":"Guglielmi O","year":"2013","journal-title":"Univ Psychol"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-016-1393-1"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arbr.2014.12.002"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.27662"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2016.07.002"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00587.2005"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12503"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12499"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-016-3703-8"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nrl.2015.03.002"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-015-1162-6"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2008.07.002"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/zsx040"},{"key":"e_1_2_8_18_1","first-page":"13","article-title":"Evaluation of compliance with continuous positive airway pressure in patients with obstructive sleep apnea syndrome","volume":"2","author":"Halvani A","year":"2017","journal-title":"J Sleep Sci"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/29.8.1031"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2016.05.015"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.3056"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2016.06.001"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2014.05.012"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12498"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-013-0806-7"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b2700"},{"key":"e_1_2_8_27_1","first-page":"425","article-title":"Doing and reporting a meta\u2010analysis","volume":"6","author":"Botella J","year":"2006","journal-title":"Int J Clin Health Psychol"},{"key":"e_1_2_8_28_1","volume-title":"Meta\u2010an\u00e1lisis en ciencias sociales y de la salud","author":"Botella J","year":"2015"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1697-2600(13)70007-3"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.6018\/analesps.34.2.320131"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.2172"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/14.6.540"},{"key":"e_1_2_8_33_1","volume-title":"Cochrane Handbook for Systematic Reviews Version 5.1.0","author":"Higgins JP","year":"2011"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/83.8.713"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1177\/1094428106291059"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1348\/000711000159150"},{"key":"e_1_2_8_37_1","volume-title":"Statistical Methods for Meta\u2010Analysis","author":"Hedges LV","year":"1985"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/0197-2456(86)90046-2"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.315.7109.629"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.86.3.638"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v036.i03"},{"key":"e_1_2_8_42_1","volume-title":"R: A Language and Environment for Statistical Computing","author":"R Development Core Team","year":"2012"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-011-0567-0"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114515004018"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2009.266"},{"key":"e_1_2_8_46_1","first-page":"1","article-title":"Improvement in obstructive sleep apnea after a tailored behavioural sleep medicine intervention targeting healthy eating and physical activity: a randomised controlled trial","author":"Igelstr\u00f6m H","year":"2017","journal-title":"Sleep Breath"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b4609"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjsem-2016-000155"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.1422"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1002\/oby.21126"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01897-2015"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.14-3016"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-009-0311-1"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.1177\/0269215511403941"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200805-669OC"},{"key":"e_1_2_8_56_1","doi-asserted-by":"crossref","first-page":"409","DOI":"10.5664\/jcsm.27594","article-title":"A diet and exercise program to improve clinical outcomes in patients with obstructive sleep apnea\u2014a feasibility study","volume":"5","author":"Barnes M","year":"2009","journal-title":"J Clin Sleep Med"},{"key":"e_1_2_8_57_1","doi-asserted-by":"publisher","DOI":"10.1080\/17461391.2012.663412"},{"key":"e_1_2_8_58_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsr.12572"},{"key":"e_1_2_8_59_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00.00014401"},{"key":"e_1_2_8_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2013.09.023"},{"key":"e_1_2_8_61_1","doi-asserted-by":"publisher","DOI":"10.1001\/2012.jama.11580"},{"key":"e_1_2_8_62_1","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0000000000000387"},{"key":"e_1_2_8_63_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.2656"},{"key":"e_1_2_8_64_1","doi-asserted-by":"publisher","DOI":"10.2486\/indhealth.MS1081"},{"key":"e_1_2_8_65_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/31.11.1527"},{"key":"e_1_2_8_66_1","doi-asserted-by":"publisher","DOI":"10.5551\/jat.17632"},{"key":"e_1_2_8_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2003.07.007"},{"key":"e_1_2_8_68_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2281.1998.00114.x"},{"key":"e_1_2_8_69_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2006.063644"},{"key":"e_1_2_8_70_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2796.1998.00387.x"},{"key":"e_1_2_8_71_1","doi-asserted-by":"publisher","DOI":"10.1097\/TIN.0b013e3181dbb7ff"},{"key":"e_1_2_8_72_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.164.6.2008010"},{"key":"e_1_2_8_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.orcp.2008.08.001"},{"key":"e_1_2_8_74_1","first-page":"121","article-title":"Exercise training effect on obstructive sleep apnea syndrome","volume":"3","author":"Norman JF","year":"2000","journal-title":"Sleep Res Online"},{"key":"e_1_2_8_75_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00103411"},{"key":"e_1_2_8_76_1","doi-asserted-by":"publisher","DOI":"10.6061\/clinics\/2013(08)17"},{"key":"e_1_2_8_77_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/32.5.637"},{"key":"e_1_2_8_78_1","first-page":"1","article-title":"The impact of alcohol on breathing parameters during sleep: a systematic review and meta\u2010analysis","author":"Kolla BP","year":"2018","journal-title":"Sleep Med Rev"},{"key":"e_1_2_8_79_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.14-0772"},{"key":"e_1_2_8_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2017.12.005"},{"key":"e_1_2_8_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2013.07.003"},{"key":"e_1_2_8_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2012.05.002"},{"key":"e_1_2_8_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1836-9553(12)70106-6"},{"key":"e_1_2_8_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijchp.2017.10.002"},{"key":"e_1_2_8_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijchp.2016.03.002"},{"key":"e_1_2_8_86_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2014.05.015"},{"key":"e_1_2_8_87_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-014-1015-8"},{"key":"e_1_2_8_88_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/zsx134"},{"key":"e_1_2_8_89_1","doi-asserted-by":"publisher","DOI":"10.1111\/cob.12180"},{"key":"e_1_2_8_90_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-017-1482-9"},{"key":"e_1_2_8_91_1","first-page":"309","article-title":"Differences between men and women in the clinical presentation of patients diagnosed with obstructive sleep apnea syndrome","volume":"28","author":"Shepertycky MR","year":"2005","journal-title":"Sleep"},{"key":"e_1_2_8_92_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2018.00220"},{"key":"e_1_2_8_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(17)30233-4"},{"key":"e_1_2_8_94_1","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.2618"},{"key":"e_1_2_8_95_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2010.29485"},{"key":"e_1_2_8_96_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d3017"},{"key":"e_1_2_8_97_1","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2005.228"},{"key":"e_1_2_8_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2013.02.005"},{"key":"e_1_2_8_99_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201710-2147ED"}],"container-title":["Obesity Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fobr.12824","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/obr.12824","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/obr.12824","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/obr.12824","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T14:21:40Z","timestamp":1694269300000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/obr.12824"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,4]]},"references-count":98,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["10.1111\/obr.12824"],"URL":"https:\/\/doi.org\/10.1111\/obr.12824","archive":["Portico"],"relation":{},"ISSN":["1467-7881","1467-789X"],"issn-type":[{"value":"1467-7881","type":"print"},{"value":"1467-789X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,4]]},"assertion":[{"value":"2018-10-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-11-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}