{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T18:16:47Z","timestamp":1789496207522,"version":"build-2803163510"},"reference-count":61,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2019,8,30]],"date-time":"2019-08-30T00:00:00Z","timestamp":1567123200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity Reviews"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Gout is characterized by high serum uric acid (SUA) levels and arthritis. It is associated with obesity and metabolic syndrome. Bariatric surgery has been associated with decreased SUA levels and overall gout incidence. This meta\u2010analysis aims to summarize the current evidence on bariatric surgery, gout and SUA levels. A literature review was performed on papers published from 2000 up till December 2018. Original studies investigating the impact of bariatric surgery on SUA levels or gout incidence were evaluated. Twenty studies with a total of 5,233 patients were analysed. Majority (n=14) had a follow\u2010up duration of at least 12 months. The mean preoperative body mass index (BMI) was 45.2kg m<jats:sup>\u22122<\/jats:sup>. The mean preoperative SUA level was 6.5mg dL<jats:sup>\u22121<\/jats:sup>. Subgroup analysis demonstrated a mean decrease in SUA levels (\u22120.73mg dL<jats:sup>\u22121<\/jats:sup>) from the third postoperative month onwards, which was sustained until the third postoperative year (\u22121.91mg dL<jats:sup>\u22121<\/jats:sup>). There was a rise in SUA levels in the first post\u2010operative month. Meta\u2010regression analyses demonstrated a proportionate linear relationship between the change in BMI and SUA levels. Post\u2010bariatric surgery weight loss is associated with reduced SUA levels and decreased incidence of gout attacks. However, this is only evident from the third post\u2010operative month onwards.<\/jats:p>","DOI":"10.1111\/obr.12940","type":"journal-article","created":{"date-parts":[[2019,8,30]],"date-time":"2019-08-30T07:41:35Z","timestamp":1567150895000},"page":"1759-1770","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":70,"title":["Impact of bariatric surgery on serum uric acid levels and the incidence of gout\u2014A meta\u2010analysis"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6717-8773","authenticated-orcid":false,"given":"Charleen","family":"Yeo","sequence":"first","affiliation":[{"name":"Department of General Surgery Tan Tock Seng Hospital  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanghvi","family":"Kaushal","sequence":"additional","affiliation":[{"name":"Department of General Surgery Tan Tock Seng Hospital  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatrice","family":"Lim","sequence":"additional","affiliation":[{"name":"Yong Loo Lin School of Medicine National University of Singapore  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Syn","sequence":"additional","affiliation":[{"name":"Yong Loo Lin School of Medicine National University of Singapore  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aung Myint","family":"Oo","sequence":"additional","affiliation":[{"name":"Department of General Surgery Tan Tock Seng Hospital  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaideepraj","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of General Surgery Tan Tock Seng Hospital  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaryan","family":"Koura","sequence":"additional","affiliation":[{"name":"Department of General Surgery Tan Tock Seng Hospital  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8028-9347","authenticated-orcid":false,"given":"Danson","family":"Yeo","sequence":"additional","affiliation":[{"name":"Department of General Surgery Tan Tock Seng Hospital  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,8,30]]},"reference":[{"issue":"6","key":"e_1_2_8_2_1","first-page":"59","article-title":"A brief history of the rheumatic diseases","volume":"32","author":"Benedek TG","year":"1982","journal-title":"Bull Rheum Dis"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60883-7"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2017-211472"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.22466"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0b013e3282f4b1ed"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-018-03676-5"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2014.01.001"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(72)92271-4"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keq256"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.165.7.742"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.59.7.539"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.21772"},{"key":"e_1_2_8_14_1","first-page":"1","article-title":"Outcomes after metabolic surgery in Asians\u2014a meta\u2010analysis","author":"Yeo D","year":"2018","journal-title":"Obes Surg"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1381\/0960892053576802"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.soard.2007.09.012"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11695-017-2984-z"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2016-209958"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b2535"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g7647"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10654-010-9491-z"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2005.06.006"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-5-13"},{"key":"e_1_2_8_24_1","volume-title":"In: Methods Guide for Effectiveness and Comparative Effectiveness Reviews. 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