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Interventions delivered by peer (lay member that participants identify with) were included. We searched 14 databases. Outcomes were combined in the meta\u2010analysis using the inverse variance random\u2010effects model. From 2435 articles, 65 articles were included in the systematic review and meta\u2010analysis (<jats:italic>n<\/jats:italic>\u00a0=\u200915,673). Peer interventions resulted in significant reduction in weight (mean difference [MD] \u22121.05\u2009kg; 95% confidence interval [CI] \u22121.68, \u22120.43; 95% prediction interval [PI] \u22123.25, 1.14; 28 studies; 7142 participants), BMI (MD \u22120.24\u2009kg\/m<jats:sup>2<\/jats:sup>; 95% CI \u22120.44, \u22120.04; 95% PI \u22120.92, 0.45; 25 studies; 6672 participants), waist circumference (MD \u22120.75\u2009cm; 95% CI \u22121.29, \u22120.21; 95% PI \u22121.36, \u22120.14; 12 studies; 4280 participants), and significant increase in physical activity (SMD 0.20; 95% CI 0.09, 0.32; 95% PI \u22120.46, 0.86; 41 studies; 10,778 participants) with no significant effect on energy intake. This study suggests peer interventions are effective in reducing waist circumference, but further research is needed to confirm its effect on other obesity\u2010related outcomes.<\/jats:p>","DOI":"10.1111\/obr.13328","type":"journal-article","created":{"date-parts":[[2021,8,13]],"date-time":"2021-08-13T12:14:58Z","timestamp":1628856898000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Peer\u2010supported lifestyle interventions on body weight, energy intake, and physical activity in adults: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5333-6451","authenticated-orcid":false,"given":"Siew","family":"Lim","sequence":"first","affiliation":[{"name":"Monash Centre for Health Research and Implementation Monash University  Clayton Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wai 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