{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T13:52:28Z","timestamp":1794059548560,"version":"4.8.0"},"reference-count":45,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,1,19]],"date-time":"2022-01-19T00:00:00Z","timestamp":1642550400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100019266","name":"Korea Medical Device Development Fund","doi-asserted-by":"publisher","award":["KMDF_PR_202012D13\u201002"],"award-info":[{"award-number":["KMDF_PR_202012D13\u201002"]}],"id":[{"id":"10.13039\/100019266","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019266","name":"Korea Medical Device Development Fund","doi-asserted-by":"publisher","award":["9991007295"],"award-info":[{"award-number":["9991007295"]}],"id":[{"id":"10.13039\/100019266","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity Reviews"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Although Roux\u2010en\u2010Y gastric bypass (RYGB) and sleeve gastrectomy (SG) are the most prevalent bariatric surgical procedures, high\u2010level evidence is scarce regarding the assessment of postoperative nutritional risk in RYGB versus SG. Therefore, we performed a systematic review and meta\u2010analysis to compare the risk of anemia and related micronutrient deficiencies after RYGB and SG. We analyzed 10 randomized controlled trials that compared RYGB and SG with reported incidence of postoperative anemia and\/or anemia\u2010related micronutrient deficiencies (iron, vitamin B<jats:sub>12<\/jats:sub>, or folate). There were no significant differences in the risk of postoperative anemia (moderate level of evidence), iron deficiency (high level of evidence), or folate deficiency (moderate level of evidence). Patients undergoing RYGB had a higher risk of postoperative vitamin B<jats:sub>12<\/jats:sub> deficiency than those undergoing SG (relative risk, 1.86; 95% confidence interval, 1.15\u20133.02; <jats:italic>p<\/jats:italic>\u2009=\u20090.012; high level of evidence). Our findings imply that patients undergoing RYGB require more stringent vitamin B<jats:sub>12<\/jats:sub> supplementation and surveillance than those undergoing SG. Additionally, our results may aid patients with high concern for anemia and related micronutrient deficiencies in making informed decisions regarding surgical methods based on nutritional risk.<\/jats:p>","DOI":"10.1111\/obr.13419","type":"journal-article","created":{"date-parts":[[2022,1,20]],"date-time":"2022-01-20T06:13:16Z","timestamp":1642659196000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":54,"title":["Comparative risk of anemia and related micronutrient deficiencies after Roux\u2010en\u2010Y gastric bypass and sleeve gastrectomy in patients with obesity: An updated meta\u2010analysis of randomized controlled trials"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4432-7403","authenticated-orcid":false,"given":"Yeongkeun","family":"Kwon","sequence":"first","affiliation":[{"name":"Division of Foregut Surgery Korea University College of Medicine  Seoul South 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University  Gyeongsan South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang Min","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Foregut Surgery Korea University College of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong\u2010Han","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Foregut Surgery Korea University College of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1779-8683","authenticated-orcid":false,"given":"Sungsoo","family":"Park","sequence":"additional","affiliation":[{"name":"Division of Foregut Surgery Korea University College of Medicine  Seoul South Korea"},{"name":"Center for Obesity and Metabolic Diseases Korea University Anam Hospital  Seoul South 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