{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T13:09:54Z","timestamp":1791724194468,"version":"4.3.4"},"reference-count":49,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T00:00:00Z","timestamp":1655251200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["no. 2017A030313855"],"award-info":[{"award-number":["no. 2017A030313855"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2017A030313855"],"award-info":[{"award-number":["2017A030313855"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity Reviews"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    This study aimed to investigate the prevalence and factors associated with secondary hyperparathyroidism (SHPT) after Roux\u2010en\u2010Y gastric bypass (RYGB). We searched PubMed, EMBASE, and CENTRAL for relevant studies using search terms gastric bypass, RYGB and hyperparathyroidism. Thirty\u2010four cohort studies with 4331 patients were incorporated into the final meta\u2010analysis. Overall estimates of the prevalence of SHPT following RYGB were 39%. Subgroup analyses indicated the pooled prevalences of SHPT were 25%, 42%, 48%, and 54% for \u22641\u2009year, &gt;1 and \u22645\u2009years, &gt;5 and \u226410\u2009years, and &gt;10\u2009years, respectively, after RYGB. Meta\u2010regression showed that SHPT occurred was positively related to follow\u2010up durations (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.001). Additionally, SHPT prevalence was higher in studies in which calcium and vitamin D supplementation were considered inadequate than in those which were adequate (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.002). SHPT is highly prevalent in individuals with obesity after RYGB. It seems to progress with time after surgery. Routine calcium and vitamin D supplementation post\u2010RYGB together with targeted treatment of vitamin D deficiency, reasonable adjustment of the doses of supplementation with regular follow\u2010up, and improved patient compliance, as well as long\u2010term screening, are necessary to prevent the development of SHPT.\n                  <\/jats:p>","DOI":"10.1111\/obr.13488","type":"journal-article","created":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T18:53:46Z","timestamp":1655319226000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Prevalence and associated factors of secondary hyperparathyroidism after Roux\u2010en\u2010Y gastric bypass: A meta\u2010analysis"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1274-5486","authenticated-orcid":false,"given":"Zhiguang","family":"Gao","sequence":"first","affiliation":[{"name":"Department of Gastrointestinal Surgery SSL Central Hospital of Dongguan City, Affiliated Dongguan Shilong People's Hospital of Southern Medical University  Dongguan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9635-1582","authenticated-orcid":false,"given":"Yuzhi","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging SSL Central Hospital of Dongguan City, Affiliated Dongguan Shilong People's Hospital of Southern Medical University  Dongguan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of General Surgery SSL Central Hospital of Dongguan City, Affiliated Dongguan Shilong People's Hospital of Southern Medical University  Dongguan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongchang","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery SSL Central Hospital of Dongguan City, Affiliated Dongguan Shilong People's Hospital of Southern Medical University  Dongguan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenpeng","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery First Affiliated Hospital of Jinan University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery SSL Central Hospital of Dongguan City, Affiliated Dongguan Shilong People's Hospital of Southern Medical University  Dongguan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shifang","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine First Affiliated Hospital of Jinan University  Guangzhou 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