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We explored associations between maternal adiposity and infant health. Searches included six databases, references, citations, and contacting authors. Screening and quality assessment were carried out by two authors independently. Random effects meta\u2010analysis and narrative synthesis were conducted. We included 34 studies (<jats:italic>n<\/jats:italic>\u00a0=\u200940,143 pregnancies). Meta\u2010analysis showed a significant association between maternal fat\u2010free mass and birthweight (average effect [AE] 18.07\u2009g, 95%CI 12.75, 23.38) but not fat mass (AE 8.76\u2009g, 95%CI \u22124.84, 22.36). Women with macrosomic infants had higher waist circumference than controls (mean difference 4.93\u2009cm, 95% confidence interval [CI] 1.05, 8.82). There was no significant association between subcutaneous fat and large for gestational age (odds ratio 1.06 95% CI 0.91, 1.25). Waist\u2010to\u2010hip ratio, neck circumference, skinfolds, and visceral fat were significantly associated with several infant outcomes including small for gestational age, preterm delivery, neonatal morbidity, and mortality, although meta\u2010analysis was not possible for these variables. Our findings suggest that some measures of maternal adiposity may be useful for risk prediction of infant outcomes. Individual participant data meta\u2010analysis could overcome some limitations in our ability to pool published data.<\/jats:p>","DOI":"10.1111\/obr.13491","type":"journal-article","created":{"date-parts":[[2022,7,8]],"date-time":"2022-07-08T08:55:50Z","timestamp":1657270550000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Association between maternal adiposity measures and infant health outcomes: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9536-0492","authenticated-orcid":false,"given":"Giang","family":"Nguyen","sequence":"first","affiliation":[{"name":"Population Health Sciences Institute Newcastle University  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6442-4150","authenticated-orcid":false,"given":"Louise","family":"Hayes","sequence":"additional","affiliation":[{"name":"Population Health Sciences Institute Newcastle University  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6920-7622","authenticated-orcid":false,"given":"Lem","family":"Ngongalah","sequence":"additional","affiliation":[{"name":"Population Health Sciences Institute Newcastle University  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theophile","family":"Bigirumurame","sequence":"additional","affiliation":[{"name":"Population Health Sciences Institute Newcastle University  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7527-5354","authenticated-orcid":false,"given":"Laura","family":"Gaudet","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Queen's University  Kingston Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1834-2696","authenticated-orcid":false,"given":"Adefisayo","family":"Odeniyi","sequence":"additional","affiliation":[{"name":"Population Health Sciences Institute Newcastle University  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8438-1506","authenticated-orcid":false,"given":"Angela","family":"Flynn","sequence":"additional","affiliation":[{"name":"Department of Nutritional Sciences King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9814-2124","authenticated-orcid":false,"given":"Lisa","family":"Crowe","sequence":"additional","affiliation":[{"name":"Population Health Sciences Institute Newcastle University  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8293-9238","authenticated-orcid":false,"given":"Becky","family":"Skidmore","sequence":"additional","affiliation":[{"name":"Independent Information Specialist  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Simon","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology University of Ottawa  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vikki","family":"Smith","sequence":"additional","affiliation":[{"name":"Nursing, Midwifery &amp; 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