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PubMed, Web of Science, and Scopus were searched from inception to March 2024 to identify original randomized trials that investigated the effects of IF versus either a control diet (CON) and\/or continuous caloric restriction (CR). Participants were adults with overweight and obesity and intervention durations were \u2265 6\u2009months. Overall, a total of 24 studies involving 2032 participants were included in the meta\u2010analysis. Compared with CON, IF significantly reduced body weight [WMD: \u22122.84\u2009kg], BMI [WMD: \u22121.41\u2009kg.m\n                    <jats:sup>2<\/jats:sup>\n                    ], fat mass [WMD: \u22123.06\u2009kg], fat\u2010free mass [WMD: \u22120.81\u2009kg], waist circumference [WMD: \u22123.85\u2009cm], visceral fat [SMD: \u22120.37], fasting glucose [WMD: \u22120.14\u2009mmol\/l], triglycerides [WMD: \u22120.12\u2009mmol\/l], and diastolic blood pressure [WMD: \u22122.24\u2009mmHg]. Conversely, IF significantly increased high\u2010density lipoproteins [WMD: 0.04\u2009mmol\/l] when compared with CON, but had no effects on insulin, hemoglobin A1c%, total cholesterol, low\u2010density lipoprotein, or systolic blood pressure. Compared with CR, IF significantly reduced fat mass [WMD: \u22120.70\u2009kg], body fat percentage [WMD: \u22120.59%], and DBP [WMD: \u22120.91\u2009mmHg], and increased HDL [WMD: 0.03\u2009mmol\/l], with no other significant effects. Subgroup analyses showed that the mode of IF and intervention duration were the primary moderators of IF effects on the markers. In adults with overweight or obesity, IF and CR are comparably effective for reducing body weight and adiposity, as well as for improving cardiometabolic health markers.\n                  <\/jats:p>","DOI":"10.1111\/obr.13855","type":"journal-article","created":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T02:29:43Z","timestamp":1730860183000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Longer\u2010term effects of intermittent fasting on body composition and cardiometabolic health in adults with overweight and obesity: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6465-1281","authenticated-orcid":false,"given":"Mousa","family":"Khalafi","sequence":"first","affiliation":[{"name":"Department of Sport Sciences, Faculty of Humanities University of Kashan  Kashan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aref Habibi","family":"Maleki","sequence":"additional","affiliation":[{"name":"Department of Exercise Physiology and Corrective Exercises, Faculty of Sport Sciences Urmia University  Urmia Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahsa","family":"Ehsanifar","sequence":"additional","affiliation":[{"name":"Department of Exercise Physiology and Corrective Exercises, Faculty of Sport Sciences Urmia University  Urmia Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael E.","family":"Symonds","sequence":"additional","affiliation":[{"name":"Centre for Perinatal Research, Academic Unit of Population and Lifespan Sciences, School of Medicine University of Nottingham  Nottingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara K.","family":"Rosenkranz","sequence":"additional","affiliation":[{"name":"Department of Kinesiology and Nutrition Sciences University of Nevada Las Vegas  Las Vegas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,11,5]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2018.3788"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2018.09.005"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2021.12.012"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1104342"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.115.306883"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23280"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.113905"},{"issue":"2","key":"e_1_2_11_9_1","first-page":"104","article-title":"Is obesity a disease or a behavior abnormality? 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