{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T18:39:34Z","timestamp":1780339174080,"version":"3.54.1"},"reference-count":42,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T00:00:00Z","timestamp":1752105600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity Reviews"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>The link between interpregnancy weight gain (IPWG) and perinatal death remains unclear. This meta\u2010analysis examines the impact of interpregnancy body mass index (BMI) increase on perinatal mortality. A comprehensive search was conducted in July 2024 across MEDLINE, Embase, Cochrane Library, and Web of Science. Observational studies quantitatively reporting IPWG and associated perinatal mortality outcomes were included. IPWG was defined as a weight gain of \u2265\u20092 BMI units or moving to a higher BMI category between consecutive pregnancies. The risk of bias was assessed using the ROBINS\u2010I tool. Random effects meta\u2010analyses were performed to generate pooled adjusted odds ratios (aORs) and 95% confidence intervals (CIs). The analysis included 10 studies (3,072,698 pregnancies). The primary outcome was perinatal death (deaths occurring at \u2265\u200920\u2009weeks of gestation up to 28\u2009days postpartum). Secondary outcomes were stillbirth (intrauterine fetal death at \u2265\u200920\u2009weeks) and neonatal death (deaths among live\u2010born infants within 28\u2009days of life). IPWG significantly increases the risk of perinatal death (aOR, 1.49; 95% CI, 1.32\u20131.69), stillbirth (aOR, 1.46; 95% CI, 1.23\u20131.72), and neonatal death (aOR, 1.39; 95% CI, 1.19\u20131.61), compared to stable interpregnancy weight. These findings suggest that IPWG may increase the risk of perinatal death, highlighting the importance of weight management counseling during the interpregnancy period.<\/jats:p>","DOI":"10.1111\/obr.13981","type":"journal-article","created":{"date-parts":[[2025,7,11]],"date-time":"2025-07-11T06:03:54Z","timestamp":1752213834000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Interpregnancy Weight Gain and Risks of Perinatal Death: A Systematic Review and Meta\u2010Analysis"],"prefix":"10.1111","volume":"26","author":[{"given":"Yu","family":"Tang","sequence":"first","affiliation":[{"name":"School of Clinical Medicine Southwest Medical University  Luzhou Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nabil","family":"Islam","sequence":"additional","affiliation":[{"name":"Department of Radiology University of Ottawa  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Luo","sequence":"additional","affiliation":[{"name":"Better Outcomes Registry &amp; 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