{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T21:18:21Z","timestamp":1791667101989,"version":"4.3.4"},"reference-count":129,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T00:00:00Z","timestamp":1765756800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T00:00:00Z","timestamp":1765756800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity Reviews"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study investigated the effects of different exercise interventions on intrahepatic lipid content and markers of glucose homeostasis and liver function in adults with and without nonalcoholic fatty liver disease (NAFLD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A comprehensive search was conducted in PubMed, Scopus, Web of Science, and EMBASE using three primary keywords including \u201cexercise training,\u201d \u201cliver fat,\u201d and \u201crandomization\u201d from inception to August 2025. Eligible studies were those that compared exercise training with either nonexercise groups or other types of exercise training.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Thirty\u2010eight studies comprising 1880 participants were included. Exercise training was more effective for reducing intrahepatic lipids [SMD: \u22120.33,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001], confirmed through subgroup analyses based on age, health status, body mass index, intervention duration, specific health status, frequency of weekly exercise sessions, biological sex, steatosis classification, and weight change%. Based on the\n                      <jats:italic>p<\/jats:italic>\n                      \u2010score rankings, the intervention that was likely to be the most effective for lowering intrahepatic lipids was high\u2010intensity interval training (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.95), followed by aerobic training (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.77), combined aerobic and resistance training (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.52), and resistance training (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.10). Secondarily, exercise training reduced fasting blood glucose [WMD: \u22122.27\u2009mg\/dL,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.007], fasting insulin [SMD: \u22120.16,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.02], glycated hemoglobin [SMD: \u22120.13,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.03], and liver function enzymes including alanine aminotransferase (ALT) [WMD: \u22123.72\u2009U\/L,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001] and aspartate aminotransferase (AST) [WMD: \u22123.51\u2009U\/L,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.02] significantly more than nonexercise groups. However, there were no significant differences in insulin resistance.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These results provide evidence of the effects of different exercise interventions as part of a healthy lifestyle for reducing intrahepatic lipids and markers of glucose dysmetabolism.<\/jats:p>\n                    <jats:p>\n                      <jats:bold>PROSPERO Registration:<\/jats:bold>\n                      CRD42025639421\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/obr.70052","type":"journal-article","created":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T02:30:18Z","timestamp":1765852218000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Comparative Efficacy of Different Exercise Interventions on Intrahepatic Lipid 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