{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T19:39:24Z","timestamp":1792179564287,"version":"4.4.0"},"reference-count":93,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T00:00:00Z","timestamp":1766707200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T00:00:00Z","timestamp":1766707200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity Reviews"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Polycystic ovarian syndrome (PCOS) is commonly associated with obesity and has cardio\u2010metabolic, reproductive, and psychiatric comorbidities. PCOS in adolescents is challenging to diagnose. Appropriate screening for PCOS among adolescents with overweight\/obesity is essential for timely diagnosis and management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      A PRISMA\u2010compliant scoping review of international and national pediatric obesity (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200932) and adolescent PCOS (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20096) management guidelines was performed to evaluate recommendations on PCOS screening and management in adolescents.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Databases searched included PubMed, MEDLINE, Embase, and CINAHL. Data were extracted from guidelines using a predefined extraction template. Guideline quality was appraised using the AGREE\u2010II instrument. Fourteen (of 32) pediatric obesity guidelines included some recommendations for PCOS evaluation, whereas six incorporated management recommendations. A summary of recommendations from reviewing PCOS\u2010specific guidelines is that all adolescent females with overweight\/obesity should be evaluated for PCOS, including a comprehensive menstrual history and clinical evaluation for hirsutism and severe acne. Free testosterone is helpful for PCOS diagnosis; ovarian ultrasound is not routinely recommended. Treatment of adolescent PCOS includes weight loss through multicomponent lifestyle or adjunct antiobesity pharmacotherapy, whereas off\u2010label use of combined oral contraceptives and metformin may be indicated for PCOS\u2010specific symptoms. Clear recommendations on PCOS in obesity guidelines are important to improve outcomes for this condition.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/obr.70072","type":"journal-article","created":{"date-parts":[[2025,12,27]],"date-time":"2025-12-27T05:49:20Z","timestamp":1766814560000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Evaluation and Management of Polycystic Ovarian Syndrome (PCOS) in Adolescents With Obesity: A Scoping Review of National and International Obesity and PCOS Management Guidelines"],"prefix":"10.1111","volume":"27","author":[{"given":"Carey\u00a0Yun\u00a0Shan","family":"Lim","sequence":"first","affiliation":[{"name":"Khoo Teck Puat\u2010National University Medical Children's Institute, Department of Paediatrics National University Health Systems  Singapore 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