{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T19:33:06Z","timestamp":1790019186042,"version":"4.0.1"},"reference-count":56,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T00:00:00Z","timestamp":1767052800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T00:00:00Z","timestamp":1767052800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity Reviews"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>This rapid review aims to summarize the evidence of weight loss following Metabolic and Bariatric Surgery (MBS) associated with preoperative comorbidities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Electronic databases Medline and EMBASE were searched for relevant articles up to and including September 2023. Studies that reported associations between the presence of comorbidities and weight loss outcomes in adult patients (age \u2265\u200918\u2009years) after MBS (with \u2265\u20096\u2009months of follow\u2010up). Standardized mean differences (SMDs) with 95% confidence intervals (95% CIs) were calculated and pooled using random effects meta\u2010analysis. Heterogeneity was quantified using the\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      statistic and tested for statistical significance using the Q\u2010statistic.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Twenty\u2010three studies published between 2001 and 2023 were reviewed. Mental illness (SMD\u2009=\u2009\u22120.33, 95% CI: \u22120.53, \u22120.13;\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u200964.72%,\n                      <jats:italic>Q<\/jats:italic>\n                      statistic\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.01), type 2 diabetes mellitus (SMD\u2009=\u2009\u22120.20, 95% CI: \u22120.36, \u22120.03;\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u200956.88%,\n                      <jats:italic>Q<\/jats:italic>\n                      statistic\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04), and sleep apnea (SMD\u2009=\u2009\u22120.28, 95% CI: \u22120.45, \u22120.12;\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u200927.39%,\n                      <jats:italic>Q<\/jats:italic>\n                      statistic\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.24) achieved slightly lower weight loss outcomes compared to those without these comorbidities. There was no significant difference in weight loss after bariatric surgery between individuals with and without preoperative hypertension (SMD\u2009=\u2009\u22120.10, 95% CI: \u22120.22, 0.03), dyslipidemia (SMD\u2009=\u2009\u22120.05, 95% CI: \u22120.20, 0.10), and metabolic syndrome (SMD\u2009=\u2009\u22120.19, 95% CI: \u22120.58, 0.19). While other comorbidities were also linked to reduced weight loss, the statistical significance of these findings was more variable.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our evidence synthesis reveals an association between the presence of several preoperative comorbidities and less favorable weight loss outcomes following MBS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/obr.70084","type":"journal-article","created":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T02:10:38Z","timestamp":1767147038000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Preoperative Comorbidities Associated With Weight Loss Following Metabolic and Bariatric Surgery: A Rapid 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University  Campbelltown New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2783-1168","authenticated-orcid":false,"given":"Milan","family":"Piya","sequence":"additional","affiliation":[{"name":"Translational Health Research Institute Western Sydney University  Campbelltown New South Wales Australia"},{"name":"School of Medicin Western Sydney University  Campbelltown New South Wales Australia"},{"name":"Diabetes Obesity Metabolism Translational Research Unit Western Sydney University  Campbelltown New South Wales Australia"},{"name":"South Western Sydney Metabolic Rehabilitation and Bariatric Program, Camden and Campbelltown Hospitals  Campbelltown New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Fahey","sequence":"additional","affiliation":[{"name":"School of Health Sciences Western Sydney University  Campbelltown New South Wales 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