{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T10:09:43Z","timestamp":1788862183989,"version":"build-2803163510"},"reference-count":82,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T00:00:00Z","timestamp":1773705600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T00:00:00Z","timestamp":1773705600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Obesity Reviews"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Resistance training (RT) effectively manages cardiometabolic risk factors in adults, but the specific effects of moderate\u2010frequency RT (2\u20133 sessions\/week) in adults with overweight or obesity are understudied.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to evaluate moderate\u2010frequency RT's effects on cardiometabolic risk factors in this population and quantify effect sizes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Sources<\/jats:title>\n                    <jats:p>PubMed, Web of Science, EMBASE, and Cochrane Library searched up to July 2025.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Eligibility<\/jats:title>\n                    <jats:p>\n                      English randomized controlled trials (RCTs) comparing RT (\u2265\u20097\u2009weeks) to nonexercise control; nonathletic adults \u2265\u200918\u2009years with BMI\u2009\u2265\u200925\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>\n                      454 participants across 12 RCTs (mean age 58.93\u2009\u00b1\u200912.87\u2009years; mean BMI 31.2\u2009\u00b1\u20093.5\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ; ~50% female).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      RT significantly reduced diastolic blood pressure (MD\u2009=\u2009\u22121.53\u2009mmHg; 95% CI: \u22122.16 to \u22120.91;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01), LDL\u2010C (MD\u2009=\u2009\u22120.25\u2009mmol\/L; 95% CI: \u22120.41 to \u22120.08;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01), and triglycerides (MD\u2009=\u2009\u22120.17\u2009mmol\/L; 95% CI: \u22120.30 to \u22120.04;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.01). No significant effects on systolic blood pressure, mean arterial pressure, waist circumference, glycemic markers, total cholesterol, or HDL\u2010C. Subgroup analyses showed larger LDL\u2010C\/triglyceride improvements with concurrent dietary control.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Moderate\u2010frequency RT inconsistently improves cardiometabolic risk factors, benefiting diastolic blood pressure, LDL\u2010C, and triglycerides but not glycemic or other parameters. Combining with dietary control may enhance benefits, supporting RT as a complementary strategy in multimodal lifestyle interventions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration PROSPERO: CRD42022343167.<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1111\/obr.70130","type":"journal-article","created":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T06:16:10Z","timestamp":1773814570000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effects of Moderate\u2010Frequency Resistance Training on Cardiometabolic Risk Factors in Adults With Overweight or Obesity: A Systematic Review and Meta\u2010Analysis"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-7716-7771","authenticated-orcid":false,"given":"Yigao","family":"Wu","sequence":"first","affiliation":[{"name":"China Institute of Sports and 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