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The review was preregistered (PROSPERO #CRD42024524026) and followed PRISMA guidelines. Searches across eight databases identified 23 randomized controlled trials, covering 18 intervention trials. Risk of bias was assessed using the Risk of Bias 2 tool. A narrative synthesis was used to cluster studies by the content of intervention and control groups. Genetic risk communication alone (no behavioral counseling, addressing nutrition and exercise) or combined with phenotype\u2010based risk was ineffective and sometimes counterproductive among low\u2010risk individuals. When combined with personalized behavioral counseling, effectiveness improved, but only when compared to waitlist control groups or non\u2010personalized behavioral counseling. Significant effects emerged in high\u2013genetic risk subgroups within personalized behavioral counseling, using behavior change techniques such as problem\u2010solving, feedback on behavior, self\u2010monitoring, and environmental changes. The most promising results emerged from complex interventions integrating genetic risk communication into multiple sessions and combining numerous additional behavioral change techniques, such as social reward, cues\/prompts, self\u2010reward. Complex personalized interventions combining multiple behavior change techniques and prompting experiential genetic risk awareness show promise for improving weight, nutrition, and exercise\u2010related outcomes.<\/jats:p>","DOI":"10.1111\/obr.70132","type":"journal-article","created":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T00:15:16Z","timestamp":1776212116000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Are There Any Effective Behavior Change Strategies for Communicating Genetic Risk in Obesity Prevention and Body Weight Reduction Interventions?"],"prefix":"10.1111","volume":"27","author":[{"given":"Zofia","family":"Szczuka","sequence":"first","affiliation":[{"name":"CARE\u2010BEH Center for Applied Research on Health Behavior and Health SWPS University  Wroclaw 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