{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T14:54:19Z","timestamp":1773672859827,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,2,14]],"date-time":"2013-02-14T00:00:00Z","timestamp":1360800000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orthod Craniofacial Res"],"published-print":{"date-parts":[[2013,8]]},"abstract":"Structured Abstract<\/jats:title>Objectives<\/jats:title>To compare the efficacy and safety of three orthodontic treatment modalities for agenesis of maxillary lateral incisors: 1) closing the space with the reshaped canine substituting the lateral incisor, 2) opening the space with placement of a conventional fixed bridge, and 3) opening the space with placement of a single\u2010unit implant and an implant\u2010supported crown.<\/jats:p><\/jats:sec>Setting<\/jats:title>Brazilian C<\/jats:styled-content>ochrane C<\/jats:styled-content>enter and U<\/jats:styled-content>niversidade F<\/jats:styled-content>ederal de S<\/jats:styled-content>\u00e3o P<\/jats:styled-content>aulo, B<\/jats:styled-content>razil.<\/jats:p><\/jats:sec>Material and Methods<\/jats:title>The following databases were investigated: C<\/jats:styled-content>ochrane R<\/jats:styled-content>egister of C<\/jats:styled-content>ontrolled T<\/jats:styled-content>rials (E<\/jats:styled-content>dition 12, 2011), EMBASE<\/jats:styled-content> (from 1974 to D<\/jats:styled-content>ecember 2011), MEDLINE<\/jats:styled-content> (from 1965 to D<\/jats:styled-content>ecember 2011), LILACS<\/jats:styled-content> (from 1966 to N<\/jats:styled-content>ovember 2011), and O<\/jats:styled-content>dontology B<\/jats:styled-content>razilian B<\/jats:styled-content>ibliography D<\/jats:styled-content>atabase (from 1966 to N<\/jats:styled-content>ovember 2011). Conference abstracts, main B<\/jats:styled-content>razilian dissertations and theses databases, and reference lists were handsearched. This systematic review included randomized or quasi\u2010randomized controlled trials (RCT<\/jats:styled-content>s) including women aged 15\u00a0years or over and men aged 21\u00a0years or over who received one of the interventions stated above. Two observers independently evaluated all the studies regarding eligibility criteria and assessed the risk of bias of included studies.<\/jats:p><\/jats:sec>Results<\/jats:title>No studies were included in the review as no RCT<\/jats:styled-content>s were found. Most of the evidence comes from case reports and narrative reviews on case reports and from three studies with a single post\u2010intervention evaluation and non\u2010comparable control groups with high risk of bias.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>There is no scientific evidence for any of the three most common types of treatment for agenesis of the maxillary lateral incisors. RCT<\/jats:styled-content>s into this issue are still necessary.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ocr.12015","type":"journal-article","created":{"date-parts":[[2013,2,14]],"date-time":"2013-02-14T08:32:41Z","timestamp":1360830761000},"page":"129-136","source":"Crossref","is-referenced-by-count":36,"title":["Treatment for agenesis of maxillary lateral incisors: a systematic review"],"prefix":"10.1111","volume":"16","author":[{"given":"D. C. M.","family":"Andrade","sequence":"first","affiliation":[{"name":"Cl\u00ednica Integrada de Odontologia (Ciodonto) Sete Lagoas Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. A.","family":"Loureiro","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Integrada de Odontologia (Ciodonto) Sete Lagoas Brazil"},{"name":"Pontif\u00edcia Universidade Cat\u00f3lica de Minas Gerais (PUC\u2010MG) Sete Lagoas Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V. E.","family":"Ara\u00fajo","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Integrada de Odontologia (Ciodonto) Sete Lagoas Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Riera","sequence":"additional","affiliation":[{"name":"Brazilian Cochrane Center Universidade Federal de S\u00e3o Paulo (UNIFESP) S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. N.","family":"Atallah","sequence":"additional","affiliation":[{"name":"Brazilian Cochrane Center Universidade Federal de S\u00e3o Paulo (UNIFESP) S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,2,14]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8240.2005.tb00076.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/bdj.2007.891"},{"key":"e_1_2_7_4_1","volume-title":"Cochrane Handbook for Systematic Reviews of Interventions: Version 5.0.2 [updated September 2009]","author":"Higgins JPT"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b2700"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2008.01698.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/22.6.697"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02170648"},{"key":"e_1_2_7_9_1","first-page":"14","article-title":"The clinical management of congenitally absent and malformed maxillary lateral incisors and second bicuspids","volume":"5","author":"Postema RS","year":"1994","journal-title":"J Gen Orthod"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3913(05)80148-9"},{"key":"e_1_2_7_11_1","first-page":"435","article-title":"Single\u2010tooth replacement: bridge vs. implant supported restoration","volume":"66","author":"Hebe l","year":"2000","journal-title":"J Can Dent Assoc"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8240.2005.tb00116.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.12968\/denu.2005.32.1.16"},{"key":"e_1_2_7_14_1","doi-asserted-by":"crossref","first-page":"592","DOI":"10.12968\/denu.2006.33.10.592","article-title":"Modern restorative management of patients with congenitally missing teeth: orthodontic and restorative considerations","volume":"33","author":"Addy L","year":"2006","journal-title":"Dental update"},{"key":"e_1_2_7_15_1","first-page":"20","article-title":"Clinical management of the congenitally missing maxillary lateral incisor and mandibular second premolar: a clinical perspective","volume":"56","author":"Angelis V","year":"2008","journal-title":"J Mass Dent Soc"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.285.15.1987"}],"container-title":["Orthodontics & Craniofacial Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Focr.12015","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ocr.12015","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T10:12:40Z","timestamp":1696241560000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ocr.12015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2,14]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["10.1111\/ocr.12015"],"URL":"https:\/\/doi.org\/10.1111\/ocr.12015","archive":["Portico"],"relation":{},"ISSN":["1601-6335","1601-6343"],"issn-type":[{"value":"1601-6335","type":"print"},{"value":"1601-6343","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,2,14]]}}}