{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T11:18:24Z","timestamp":1793531904394,"version":"4.5.0"},"reference-count":20,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2015,4,9]],"date-time":"2015-04-09T00:00:00Z","timestamp":1428537600000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"United States National Institute for Dental and Craniofacial Research","award":["R01DE016417"],"award-info":[{"award-number":["R01DE016417"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orthod Craniofacial Res"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:title>Structured Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Cartilage fatigue, due to mechanical work, may account for precocious development of degenerative joint disease in the temporomandibular joint (<jats:styled-content style=\"fixed-case\">TMJ<\/jats:styled-content>). This study compared energy densities (mJ\/mm\u00b3) in <jats:styled-content style=\"fixed-case\">TMJ<\/jats:styled-content>s of three diagnostic groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting and Sample Population<\/jats:title><jats:p>Sixty\u2010eight subjects (44 women, 24 men) gave informed consent. Diagnostic criteria for temporomandibular disorders (<jats:styled-content style=\"fixed-case\">DC<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">TMD<\/jats:styled-content>) and imaging were used to group subjects according to presence of jaw muscle or joint pain (+<jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>) and bilateral disk displacement (+<jats:styled-content style=\"fixed-case\">DD<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>Subjects (+<jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>+<jats:styled-content style=\"fixed-case\">DD<\/jats:styled-content>,<jats:italic> n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>16; \u2013<jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>+<jats:styled-content style=\"fixed-case\">DD<\/jats:styled-content>,<jats:italic> n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>16; and \u2013<jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>\u2013<jats:styled-content style=\"fixed-case\">DD<\/jats:styled-content>,<jats:italic> n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>36) provided cone\u2010beam computed tomography and magnetic resonance images, and jaw\u2010tracking data. Numerical modeling was used to determine <jats:styled-content style=\"fixed-case\">TMJ<\/jats:styled-content> loads (<jats:italic><jats:styled-content style=\"fixed-case\">F<\/jats:styled-content><\/jats:italic><jats:sub>normal<\/jats:sub>). Dynamic stereometry was used to characterize individual\u2010specific data of stress\u2010field dynamics during 10 symmetrical jaw\u2010closing cycles. These data were used to estimate tractional forces (<jats:italic><jats:styled-content style=\"fixed-case\">F<\/jats:styled-content><\/jats:italic><jats:sub>traction<\/jats:sub>). Energy densities were then calculated as <jats:italic><jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">Q<\/jats:styled-content><\/jats:italic> (<jats:italic>W<\/jats:italic>\u00a0=\u00a0work done or mechanical energy input=tractional force\u00a0\u00d7\u00a0distance of stress\u2010field translation, <jats:italic>Q<\/jats:italic>\u00a0=\u00a0volume of cartilage). <jats:sc>anova<\/jats:sc> and <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>ukey\u2013<jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>ramer <jats:italic>post hoc<\/jats:italic> analyses tested for intergroup differences.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean\u00a0\u00b1\u00a0standard error energy density for the +P+<jats:styled-content style=\"fixed-case\">DD<\/jats:styled-content> group was 12.7\u00a0\u00b1\u00a01.5\u00a0mJ\/mm\u00b3 and significantly greater (all adjusted p\u00a0&lt;\u00a00.04) when compared to \u2013<jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>+<jats:styled-content style=\"fixed-case\">DD<\/jats:styled-content> (7.4\u00a0\u00b1\u00a01.4\u00a0mJ\/mm\u00b3) and \u2013P\u2013<jats:styled-content style=\"fixed-case\">DD<\/jats:styled-content> (5.8\u00a0\u00b1\u00a00.9\u00a0mJ\/mm\u00b3) groups. Energy densities in \u2013P+<jats:styled-content style=\"fixed-case\">DD<\/jats:styled-content> and \u2013P\u2013<jats:styled-content style=\"fixed-case\">DD<\/jats:styled-content> groups were not significantly different.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Diagnostic group differences in energy densities suggest that mechanical work may be a unique mechanism, which contributes to cartilage fatigue in subjects with pain and disk displacement.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ocr.12074","type":"journal-article","created":{"date-parts":[[2015,4,11]],"date-time":"2015-04-11T00:45:13Z","timestamp":1428713113000},"page":"164-169","source":"Crossref","is-referenced-by-count":24,"title":["Diagnostic group differences in temporomandibular joint energy densities"],"prefix":"10.1111","volume":"18","author":[{"given":"L. M.","family":"Gallo","sequence":"first","affiliation":[{"name":"Center of Dental Medicine Clinic of Masticatory Disorders, Removable Prosthodontics, Geriatric and Special Care Dentistry University of Zurich Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. R.","family":"Iwasaki","sequence":"additional","affiliation":[{"name":"Departments of Orthodontics &amp; Dentofacial Orthopedics, and Oral &amp; Craniofacial Sciences School of Dentistry University of Missouri\u2010Kansas City Kansas City MO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y. M.","family":"Gonzalez","sequence":"additional","affiliation":[{"name":"Department of Oral Diagnostic Sciences School of Dental Medicine University at Buffalo Buffalo NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Liu","sequence":"additional","affiliation":[{"name":"Departments of Orthodontics &amp; Dentofacial Orthopedics, and Oral &amp; Craniofacial Sciences School of Dentistry University of Missouri\u2010Kansas City Kansas City MO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. B.","family":"Marx","sequence":"additional","affiliation":[{"name":"Department of Statistics University of Nebraska\u2010Lincoln Lincoln NE USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. C.","family":"Nickel","sequence":"additional","affiliation":[{"name":"Departments of Orthodontics &amp; Dentofacial Orthopedics, and Oral &amp; Craniofacial Sciences School of Dentistry University of Missouri\u2010Kansas City Kansas City MO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,4,9]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10439-009-9685-2"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1115\/1.4007177"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10439-010-0099-y"},{"key":"e_1_2_8_5_1","first-page":"427","volume-title":"Temporomandibular Disorders and Orofacial Pain \u2013 Separating Controversy from Consensus","author":"Nickel JC","year":"2009"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2004.11.012"},{"key":"e_1_2_8_7_1","first-page":"160","article-title":"Mechanical response of the porcine temporomandibular joint disc to an impact event and repeated tensile loading","volume":"17","author":"Beatty MW","year":"2003","journal-title":"J Orofac Pain"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034512468749"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0722.2006.00265.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034510364492"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9290(94)90044-2"},{"key":"e_1_2_8_12_1","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.2106\/00004623-196749060-00005","article-title":"Lubrication of animal joints. I. The arthrotripsometer","volume":"49","author":"Linn FC","year":"1967","journal-title":"J Bone Joint Surg"},{"key":"e_1_2_8_13_1","first-page":"301","article-title":"Research diagnostic criteria for temporomandibular disorders: review, criteria, examinations and specifications, critique","volume":"6","author":"Dworkin SF","year":"1992","journal-title":"J Craniomandib Disord"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2009.02.023"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1159\/000086199"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034509340161"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.4081\/or.2009.e29"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034512445909"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034511415275"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/ocr.12085"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/joor.12112"}],"container-title":["Orthodontics &amp; Craniofacial Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Focr.12074","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ocr.12074","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T07:47:42Z","timestamp":1694591262000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ocr.12074"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4]]},"references-count":20,"journal-issue":{"issue":"S1","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["10.1111\/ocr.12074"],"URL":"https:\/\/doi.org\/10.1111\/ocr.12074","archive":["Portico"],"relation":{},"ISSN":["1601-6335","1601-6343"],"issn-type":[{"value":"1601-6335","type":"print"},{"value":"1601-6343","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4]]}}}