{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T01:21:00Z","timestamp":1780363260155,"version":"3.54.1"},"reference-count":32,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2015,4,9]],"date-time":"2015-04-09T00:00:00Z","timestamp":1428537600000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"United States National Institute for Dental and Craniofacial Research","award":["R01DE016417"],"award-info":[{"award-number":["R01DE016417"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orthod Craniofacial Res"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:title>Structured Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Subjects with\/without temporomandibular joint disorders (<jats:styled-content style=\"fixed-case\">TMJD<\/jats:styled-content>) were tested for differences in muscle forces.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting and Sample Population<\/jats:title><jats:p>School of Dental Medicine, University at Buffalo. Ninety\u2010one subjects were classified in four groups based on the presence\/absence (\u00b1) of chronic myofascial and\/or <jats:styled-content style=\"fixed-case\">TMJ<\/jats:styled-content> pain (P) and bilateral disc displacement (<jats:styled-content style=\"fixed-case\">DD<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>Validated numerical models employed an organizational objective and subjects' anatomy to calculate masticatory muscle forces during static biting. <jats:sc>anova<\/jats:sc> and Holm's step\u2010down procedure <jats:italic>post hoc<\/jats:italic> tests assessed group differences. Theoretical geometries, representing the range of subjects' muscle orientations, were surveyed via numerical models to identify key combinations resulting in high muscle forces. Effect size (Cohen's <jats:italic>d<\/jats:italic>) and <jats:sc>anova<\/jats:sc>\/<jats:italic>post hoc<\/jats:italic> tests assessed group differences in key muscle orientations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>+P\u2212<jats:styled-content style=\"fixed-case\">DD<\/jats:styled-content> subjects had significantly higher muscle forces, especially for lateral pterygoid muscles, compared to the other groups (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.01) for bite forces that were directed posteromedially or posterolaterally on mandibular molars and posteriorly and slightly medially on mandibular incisors. Key muscle orientations for peak lateral pterygoid muscle forces were identified, and group comparisons showed mean orientation in +P\u2212<jats:styled-content style=\"fixed-case\">DD<\/jats:styled-content> compared to other diagnostic groups was \u22655\u00b0 more upright for masseter and \u22653\u00b0 more posteriorly directed for temporalis muscles (all Cohen's <jats:italic>d<\/jats:italic>\u00a0\u2265\u00a00.8).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Predicted lateral pterygoid muscle forces were significantly higher in +P\u2212<jats:styled-content style=\"fixed-case\">DD<\/jats:styled-content> compared to other groups for specific biting conditions and were attributable, in part, to differences in masseter and temporalis muscle orientations.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ocr.12075","type":"journal-article","created":{"date-parts":[[2015,4,11]],"date-time":"2015-04-11T00:45:13Z","timestamp":1428713113000},"page":"170-179","source":"Crossref","is-referenced-by-count":11,"title":["Modeling of muscle forces in humans with and without temporomandibular joint disorders"],"prefix":"10.1111","volume":"18","author":[{"given":"L. R.","family":"Iwasaki","sequence":"first","affiliation":[{"name":"Departments of Orthodontics &amp; Dentofacial Orthopedics and Oral &amp; Craniofacial Sciences University of Missouri\u2010Kansas City Kansas City MO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Liu","sequence":"additional","affiliation":[{"name":"Departments of Orthodontics &amp; Dentofacial Orthopedics and Oral &amp; Craniofacial Sciences University of Missouri\u2010Kansas City Kansas City MO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y. M.","family":"Gonzalez","sequence":"additional","affiliation":[{"name":"Department of Oral Diagnostic Sciences University at Buffalo Buffalo NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. B.","family":"Marx","sequence":"additional","affiliation":[{"name":"Department of Statistics University of Nebraska\u2010Lincoln Lincoln NE USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. C.","family":"Nickel","sequence":"additional","affiliation":[{"name":"Departments of Orthodontics &amp; Dentofacial Orthopedics and Oral &amp; Craniofacial Sciences University of Missouri\u2010Kansas City Kansas City MO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,4,9]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9290(94)00128-Q"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345880670060201"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2009.02.027"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034510364492"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.4081\/or.2009.e29"},{"key":"e_1_2_8_7_1","first-page":"427","volume-title":"Temporomandibular Disorders and Orofacial Pain \u2013 Separating Controversy from Consensus","author":"Nickel JC","year":"2009"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2007.10.002"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-9969(03)00171-7"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2007.06.640"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2009.12.013"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034512445909"},{"key":"e_1_2_8_13_1","first-page":"301","article-title":"Research diagnostic criteria for temporomandibular disorders: review, criteria, examinations and specifications, critique","volume":"6","author":"Dworkin SF","year":"1992","journal-title":"J Craniomandib Disord"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2009.02.023"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0722.2008.00560.x"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9969(92)90119-S"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345920710010801"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00230303"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016357.2011.597778"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.sodo.2011.10.001"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00653.2011"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00221-013-3729-4"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00221-012-3219-0"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345930720050801"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345950740061201"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-4328(02)00151-1"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1139\/y91-102"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2012.0068"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/joor.12112"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1834-7819.2008.00050.x"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034512470832"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2011.09.001"},{"key":"e_1_2_8_33_1","first-page":"7","article-title":"Biopsychosocial factors associated with the subcategories of acute temporomandibular joint disorders","volume":"26","author":"Dougall AL","year":"2012","journal-title":"J Orofac Pain"}],"container-title":["Orthodontics &amp; Craniofacial Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Focr.12075","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ocr.12075","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T07:47:46Z","timestamp":1694591266000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ocr.12075"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4]]},"references-count":32,"journal-issue":{"issue":"S1","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["10.1111\/ocr.12075"],"URL":"https:\/\/doi.org\/10.1111\/ocr.12075","archive":["Portico"],"relation":{},"ISSN":["1601-6335","1601-6343"],"issn-type":[{"value":"1601-6335","type":"print"},{"value":"1601-6343","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4]]}}}