{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T16:11:13Z","timestamp":1790784673552,"version":"4.1.0"},"reference-count":36,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,2,16]],"date-time":"2017-02-16T00:00:00Z","timestamp":1487203200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orthod Craniofacial Res"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:title>Structured Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>In children with Down syndrome, the timing of dental eruption is important for orthodontics treatment planning. Aim of this study was to determine whether tooth eruption and development of the dentition in children with Down syndrome are impaired.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>Dental development was scored on orthopantomograms (<jats:styled-content style=\"fixed-case\">OPT<\/jats:styled-content>s) of 95 children with Down syndrome. The dental age was determined at the left mandibular side according to the Demirjian method and by converting the assigned scores to the dental maturity score. Dental development scores of control children and <jats:styled-content style=\"fixed-case\">DS<\/jats:styled-content> children were compared with a mixed model linear regression analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The model showed statistically significant changes relating to increasing age (<jats:italic>P<\/jats:italic>&lt;0.001) and gender (<jats:italic>P<\/jats:italic>&lt;0.05). In this comparison, the total <jats:styled-content style=\"fixed-case\">DS<\/jats:styled-content> group (with and without hypodontia) was not statistically significantly different from the control group. There was also no significant difference between the total sample of <jats:styled-content style=\"fixed-case\">DS<\/jats:styled-content> children and the control group after using the Nystr\u00f6m imputation (with and without hypodontia).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The findings showed that dental development in <jats:styled-content style=\"fixed-case\">DS<\/jats:styled-content> children is similar to the development of control children and that a relationship exists between hypodontia and dental development. The clinically observed late eruption is probably not due to late dental development but due to the other processes that take place during eruption, such as the possible impaired processes at the apical side and the occlusal side of an erupting element.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ocr.12139","type":"journal-article","created":{"date-parts":[[2017,2,16]],"date-time":"2017-02-16T13:42:37Z","timestamp":1487252557000},"page":"65-70","source":"Crossref","is-referenced-by-count":14,"title":["Dental development in Down syndrome and healthy children: a comparative study using the Demirjian method"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5206-0617","authenticated-orcid":false,"given":"M. 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