{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T11:26:40Z","timestamp":1740137200489,"version":"3.37.3"},"reference-count":31,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,9,5]],"date-time":"2017-09-05T00:00:00Z","timestamp":1504569600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orthod Craniofacial Res"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>Structured Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Studies have shown that the mandibular permanent first molar (M1<jats:sub>inf<\/jats:sub>) in young children with isolated cleft palate is characterized by delay in maturation and has reduced crown width. Consequently, it is of interest to investigate the early maturation and width of the follicle and crown of M1<jats:sub>inf<\/jats:sub> in children with combined cleft lip and palate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Retrospective, longitudinal study. Cephalometric X\u2010rays of 47 consecutive Danish children with <jats:styled-content style=\"fixed-case\">UCCLP<\/jats:styled-content> (37 males; 10 females) and 44 with unilateral incomplete cleft lip (<jats:styled-content style=\"fixed-case\">UICL<\/jats:styled-content>) (29 males; 15 females) examined at 2 and 22\u00a0months of age. <jats:styled-content style=\"fixed-case\">UICL<\/jats:styled-content> served as control group. Maturation (according to Haavikko), width of follicle (<jats:styled-content style=\"fixed-case\">FW<\/jats:styled-content>) and crown (<jats:styled-content style=\"fixed-case\">CW<\/jats:styled-content>) of M1<jats:sub>inf<\/jats:sub> were assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The maturation of the first mandibular molar was delayed in both genders at 2 and 22\u00a0months of age. <jats:styled-content style=\"fixed-case\">FW<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">CW<\/jats:styled-content> were smaller in children with <jats:styled-content style=\"fixed-case\">UCCLP<\/jats:styled-content> at both 2 and 22\u00a0months of age. There was a positive correlation between maturation and <jats:styled-content style=\"fixed-case\">FW<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Maturation of the first mandibular molar is delayed in both genders, and <jats:styled-content style=\"fixed-case\">FW<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">CW<\/jats:styled-content> were reduced in <jats:styled-content style=\"fixed-case\">UCCLP<\/jats:styled-content> compared to controls. Maturation was correlated with <jats:styled-content style=\"fixed-case\">FW<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ocr.12197","type":"journal-article","created":{"date-parts":[[2017,9,5]],"date-time":"2017-09-05T13:56:42Z","timestamp":1504619802000},"page":"196-201","source":"Crossref","is-referenced-by-count":3,"title":["Early post\u2010natal development of the mandibular permanent first molar in infants with unilateral complete cleft lip and palate"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8079-8571","authenticated-orcid":false,"given":"N. 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